Results 131 to 140 of about 101,993 (329)

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

The FEBS Journal, EarlyView.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari, Kathryn Volkening, Zahra Nayeri, Aysegul Yucel Polat, Neil Donison, Jacqueline Palik, Michael J. Strong   +6 more
wiley   +1 more source

Development of NP-Based Universal Vaccine for Influenza A Viruses

Vaccines
The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8+ cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes.
Ekramy E. Sayedahmed, Nelly O. Elshafie, Andrea P. dos Santos, Chinnaswamy Jagannath, Suryaprakash Sambhara, Suresh K. Mittal   +5 more
doaj   +1 more source

The Inability to Disassemble Rad51 Nucleoprotein Filaments Leads to Aberrant Mitosis and Cell Death [PDF]

, 2023
Tadas Andriuskevicius, Anton Dubenko, Svetlana Makovets   +2 more
openalex   +1 more source

Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF‐κB pathway

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen, Sheng Xu, Bingrong Chen, Xishan Xiong, Jinrui Hu, Yuhong Wu, Tianrui Wang, Huishang Wang   +7 more
wiley   +1 more source

Rabies virus nucleoprotein: large-scale expression in prokaryotic system

Macedonian Veterinary Review
Rabies is controlled by mass animal vaccination campaigns. Cats, dogs, and wild animals (e.g., bats) are large reservoirs of this virus and can pose a significant threat to the human health, especially in the developing countries.
Leandro Daniel Picotto, Carlos Javier Panei, Marcelo Ricardo Pecoraro, Guillermo Hernán Sguazza   +3 more
doaj   +1 more source

Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]

, 2012
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core  

Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy [PDF]

, 2016
A case of pleuropneumonia is reported in an adult male bottlenose dolphin (Tursiops truncatus) found stranded in 2014 along the Central Adriatic coast of Italy.
Camm\ue0, Cesare, Curini, Valentina, Di Francesco, Cristina Esmeralda, Di Francesco, Gabriella, Di Guardo, Giovanni, Di Provvido, Andrea, Ferri, Nicola, Mazzariol, Sandro, Proietto, Umberto   +8 more
core   +1 more source

Review of expansion microscopy combined with advanced imaging modalities

Journal of Microscopy, EarlyView.
Abstract Expansion microscopy (ExM) is a powerful high‐resolution imaging technique that enhances the spatial resolution of conventional light microscopy by physically enlarging biological specimens by embedding and cross‐linking them in a swellable polymer network.
Natalie Woo, Claire M. Brown
wiley   +1 more source

Diversifying T-cell responses: safeguarding against pandemic influenza with mosaic nucleoprotein

Journal of Virology
Pre-existing T-cell responses have been linked to reduced disease severity and better clinical outcomes during the 2009 influenza pandemic and the recent COVID-19 pandemic.
Hongtae Park, Brock Kingstad-Bakke, Thomas Cleven, Myunghwan Jung, Yoshihiro Kawaoka, M. Suresh   +5 more
doaj   +1 more source

Biomphalaria alexandrina snails as immunogens against Schistosoma mansoni infection in mice

Memorias do Instituto Oswaldo Cruz, 2010
Despite effective chemotherapy, schistosomiasis remains the second largest public health problem in the developing world. Currently, vaccination is the new strategy for schistosomiasis control.
Manal A Hamed, Sanaa A Ali, Hanan F Aly, Nagy Saba El-Rigal, Maha Z Rizk   +4 more
doaj   +1 more source