Results 111 to 120 of about 60,064 (253)

To be or not to be phosphorylated: understanding the role of Ebola virus nucleoprotein in the dynamic interplay with the transcriptional activator VP30 and the host phosphatase PP2A-B56

Emerging Microbes and Infections
Ebola virus (EBOV) transcription is essentially regulated via dynamic dephosphorylation of its viral transcription activator VP30 by the host phosphatase PP2A.
Lennart Kämper, Ida Kuhl, Melina Vallbracht, Thomas Hoenen, Uwe Linne, Axel Weber, Petr Chlanda, Michael Kracht, Nadine Biedenkopf   +8 more
doaj   +1 more source

Quantum‐Level Influences on Enzyme Reactions and Their Ripple Effects on Biological Phenomena

Advanced Physics Research, Volume 5, Issue 9, September 2026.
Because living organisms are ultimately composed of atoms and molecules, quantum‐mechanical effects are expected to contribute to biological phenomena. Quantum biology seeks to elucidate life processes from a quantum‐mechanical perspective. This review discusses how quantum‐level effects, including quantum tunneling, may propagate from enzymatic proton‐
Takeshi Yasuda
wiley   +1 more source

Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization

Frontiers in Immunology
IntroductionThere is an urgent need for influenza vaccine strategies that enhance protection against influenza virus drift and across different subtypes. The conserved viral nucleoprotein (NP) is the most abundant viral protein during replication, and a
Ebony N. Gary, Abigail R. Trachtman, Dan Wang, Suman Bharti, Ying Ye, Nicholas J. Tursi, Nicholas J. Tursi, Martina Tomirotti, Martina Tomirotti, Jillian Eisenhauer, Jillian Eisenhauer, Jacqueline D. Chu, David Custodio Zegarra, Casey E. Hojecki, Micki Zheng, Micki Zheng, Jayamanna Wickramasinghe, David B. Weiner, Ami Patel   +18 more
doaj   +1 more source

The Role of Arp2/3 in End‐Resection During DNA Double‐Strand Break Repair

BioEssays, Volume 48, Issue 9, September 2026.
Arp2/3 has an evolutionarily conserved role in promoting 5’ to 3’ resection of DSBs, RAD51 filament formation, maintenance of the DNA damage checkpoint, increased mobility of DSBs, and relocation of damage in heterochromatin regions to the nuclear periphery.
Felix Y. Zhou, James E. Haber
wiley   +1 more source

Purified influenza virus nucleoprotein protects mice from lethal infection

, 1987
SUMMARY Local administration of nucleoprotein purified from X31 (H3N2) influenza A virus primed for A virus cross-reactive cytotoxic T cells and resulted in substantial protection (75 ~) of mice from a lethal challenge with the heterologous mouse-adapted
Angela E Vessey, David C Wraith, Brigitte A Askonas   +2 more
core  

Combining RNA-DNA swapping and quantitative polymerase chain reaction for the detection of influenza A nucleoprotein

, 2012
The detection of proteinaceous antigens generally relies on traditional immunoassays and, more recently, on immuno-PCR (polymerase chain reaction) assays and their derivatives, which do not take advantage of the intrinsic function or binding property of ...
Patrick M. Schaeffer, Schaeffer, Patrick M., Morin, Isabelle, Isabelle Morin   +3 more
core   +1 more source

Separation of nucleoprotein complexes with antioxidant activity from yeast Saccharomyces cerevisiae

, 2007
In this study, complexes of nucleic acids and acidic nuclear proteins were isolated from baker's yeast cells of Saccharomyces cerevisiae by mild alkaline extraction followed by precipitation with acetic acid. The optimal composition of the buffer applied
Butylina, Svetlana,, Shataeva, Larisa K.,, Nyström, Marianne,   +2 more
core   +1 more source

MiR-130c-5p targets the SHVV n gene and upregulates immune cytokines (IL-6, IL-22, IL-1β) to inhibit viral replication

Frontiers in Immunology
BackgroundSnakehead vesiculovirus (SHVV) has led to huge economic losses in snakehead aquaculture, and its pathogenic mechanisms is still not fully understood.
Jin Wei, Yan Ji, Yaqian Bai, Rui Cheng, Jiaqi Zhang, Xianqin Hu, Chi Zhang   +6 more
doaj   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

Equine Veterinary Journal, Volume 58, Issue 5, Page 1269-1282, September 2026.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock, John Grewar, Richard Newton   +2 more
wiley   +1 more source

Epitope identification of rabies virus nucleoprotein using immunoinformatics approach [PDF]

Background Rabies is a deadly and preventable disease. The nucleoprotein of rabies virus has been found to have group-specific antigenic determinants. The rabies virus nucleoprotein can shield dogs and mice from the lethal infection.
Shueb, Mohammad, Isloor, Shrikrishna, Sannejal, Akhila D, Devegowda, Devananda, Manjunatha, Kavitha G, Prasad, Shashanka K, Chethana, Chandrahasa, Pinto, Deepak S   +7 more
core   +1 more source