Results 111 to 120 of about 81,602 (239)

Fetuin‐b Mediates Lipid Overload‐Induced Hepatic Lipid Accumulation in Large Yellow Croaker (Larimichthys crocea)

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Schematic of the mechanism of fetuin‐b mediated high‐fat diet‐induced hepatic steatosis in Larimichthys crocea. Lipid overload triggers C/EBPα‐mediated fetuin‐b upregulation. Fetuin‐b drives hepatic lipid accumulation by reprogramming lipid metabolism and inhibiting Plin2 ubiquitination to stabilize lipid droplets, identifying it as a potential ...
Yanan Shen   +8 more
wiley   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh   +3 more
wiley   +1 more source

High-Mobility-Group protein I can modulate binding of transcription factors to the U5 region of the human immunodeficiency virus Type 1 proviral promoter [PDF]

open access: yes, 2000
HMG I/Y appears to be a multifunctional protein that relies on in its ability to interact with DNA in a structure-specific manner and with DNA, binding transcriptional activators via distinct protein-protein interaction surfaces.
Henderson, A.   +4 more
core   +1 more source

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein

open access: yesFrontiers in Immunology
Complement activation is considered to contribute to the pathogenesis of severe SARS-CoV-2 infection, mainly by generating potent immune effector mechanisms including a strong inflammatory response.
Isabelle Bally   +15 more
doaj   +1 more source

Nucleoproteins of Cell Nuclei [PDF]

open access: yesProceedings of the National Academy of Sciences, 1942
A E, Mirsky, A W, Pollister
openaire   +2 more sources

SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses

open access: yesMicrobiology Spectrum
Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response.
Ze-zheng Jiang   +9 more
doaj   +1 more source

Integrating heterogeneous knowledges for understanding biological behaviors: a probabilistic approach [PDF]

open access: yes, 2007
Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations.
Bourdon, Jérémie   +3 more
core   +2 more sources

Structural Impact of the Interaction of the Influenza A Virus Nucleoprotein with Genomic RNA Segments

open access: yesViruses
Influenza A viruses (IAVs) possess a segmented genome consisting of eight viral RNAs (vRNAs) associated with multiple copies of viral nucleoprotein (NP) and a viral polymerase complex.
Erwan Quignon   +8 more
doaj   +1 more source

Canine distemper virus infection in a lesser grison (Galictis cuja): first report and virus phylogeny Infecção pelo vírus da cinomose canina em um furão (Galictis cuja): primeiro relato e filogenia viral

open access: yesPesquisa Veterinária Brasileira, 2013
Infectious diseases in wild animals have been increasing as a result of their habitat alterations and closer contact with domestic animals. Canine distemper virus (CDV) has been reported in several species of wild carnivores, presenting a threat to ...
Jane Megid   +7 more
doaj  

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