Results 131 to 140 of about 60,064 (253)

Conditional eIF2A Deletion Suggests Extra‐Adipose Mechanisms Underlying Metabolic Syndrome in Total‐Body eIF2A Knockout Mice

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Adipose tissue‐specific deficiency of eIF2A is insufficient to reproduce the metabolic defects observed in total‐body eIF2A knockout mice, suggesting that the systemic metabolic effects observed in these mice may arise from coordinated functions across multiple organs.
Adedeji Isaac Adeloye, Richard Anderson, Anchal Agarwal, Barsanjit Mazumder, Taras Y. Nazarko, Atefeh Bagheri, Archana Prabahar, Peng Jiang, Frank Tedeschi, William C. Merrick, David A. Buchner, Maria Hatzoglou, Roman V. Kondratov, Anton A. Komar   +13 more
wiley   +1 more source

Analysis of herpes simplex virus nucleoprotein complexes extracted from infected cells

, 1980
HEp-2 cells were infected with herpes simplex virus type 1 and labeled with [3H]thymidine and 14C-amino acids. Infected cells or nuclei prepared from them were extracted with Triton X-100 and NaCl, utilizing a method recently described, and the low-speed
PIGNATTI, Pierfranco, E. Cassai
core   +1 more source

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein

Frontiers in Immunology
Complement activation is considered to contribute to the pathogenesis of severe SARS-CoV-2 infection, mainly by generating potent immune effector mechanisms including a strong inflammatory response.
Isabelle Bally, Guillaume Drumont, Véronique Rossi, Serafima Guseva, Maiia Botova, Jean-Baptiste Reiser, Michel Thépaut, Sebastian Dergan Dylon, Chantal Dumestre-Pérard, Chantal Dumestre-Pérard, Christine Gaboriaud, Franck Fieschi, Martin Blackledge, Pascal Poignard, Pascal Poignard, Nicole M. Thielens   +15 more
doaj   +1 more source

Nucleoproteins of white clover [PDF]

Biochemical Journal, 1960
openaire   +2 more sources

Prenatal Alcohol Exposure Produces Selective Changes in Neuroimmune Gene Expression Across Brain Regions of Adult Mice

Alcohol, Clinical and Experimental Research, Volume 50, Issue 9, September 2026.
PAE creates a unique inflammatory signature in the mature adult brain with region‐specific changes in genes implicated in glial‐immune function. We report at least 60 differentially expressed genes in different brain regions due to PAE, many of which are associated with neuroimmune function.
Alissa N. Jones, Ariana N. Pritha, Ashlynn M. Aguilar, Andrea A. Pasmay, Justin R. Carter, Nikolaos Mellios, Shahani Noor   +6 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, Volume 293, Issue 17, Page 5340-5362, September 2026.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Respiratory and systematic humoral and cellular immune response of pigs to a heterosubtypic influenza A virus infection [PDF]

, 2001
The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2.
Heinen, P.P., de Boer Luijtze, E.A., Boer Luijtze, E.A., de, Bianchi, A.T.J.   +3 more
core  

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

The FEBS Journal, Volume 293, Issue 17, Page 5383-5395, September 2026.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang, Somaieh Ahmadian, Jolanda Piepers, Florian Bock, Tom Keulers, Marc A. Vooijs   +5 more
wiley   +1 more source

BLIMP‐1 and CD39 expression define human effector memory regulatory T cells in blood and recall responses to viruses

Immunology &Cell Biology, Volume 104, Issue 8, Page 757-767, September 2026.
This study found that BLIMP‐1 is highly expressed in activated effector/memory human regulatory T cells, especially CD39+ Tregs, where it is associated with increased IL‐10 production and a conserved phenotype across blood and lung tissues during immune responses such as SARS‐CoV‐2 infection.
Chansavath Phetsouphanh, Laura Cook, Katherine J. L. Jackson, Deirdre Cuff, Vera Klemm, Bikash Manandhar, Denise C. Hsu, Yin Xu, John J. Zaunders, Anthony D. Kelleher, Nabila Seddiki   +10 more
wiley   +1 more source

H5N1 Clade 2.3.4.4b Infections in Domestic Cats During an Avian Influenza Outbreak in Italy: Implications for One Health Surveillance

Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Background H5Nx goose/Guangdong (Gs/GD) lineage highly pathogenic avian influenza (HPAI) viruses pose a significant public health threat due to their global spread, mutation accumulation, and expanding host range. The descendant clade 2.3.4.4b has been causing widespread infections in birds and increasing spillover events in mammals.
Giulia D'Annunzio, Ana Moreno, Giovanni Tosi, Patrizia Bassi, Alessio Bortolami, Giuseppe Diegoli, Alessandra Drago, Alice Fusaro, Luca Gelmini, Lucia Rita Gibelli, Tiziana Lazzarotto, Elisabetta Lilliu, Luisa Loli Piccolomini, Andrea Maroni, Enrica Martini, Giulio Matteo, Giovanna Mattei, Luisa Vera Muscatello, Isabella Monne, Elisa Palumbo, Giorgia Prezzemolo, Valentina Ravaioli, Davide Resi, Luigi Ruocco, Michele Ottavio Sabatino, Enrico Savegnago, Marco Sordilli, Calogero Terregino, Clara Tolini, Giuseppe Merialdi   +29 more
wiley   +1 more source