Results 121 to 130 of about 55,866 (243)

Study on the immune enhancers against Micropterus salmoides rhabdovirus infection

open access: yesJournal of Limnology
Micropterus salmoides rhabdovirus (MSRV) is one of the most serious pathogens harming M. salmoides juvenile, which had brought huge economic losses to farming industry. Studies involving candidate genes to the clinical diseases, however, are limited. In
Ning Lei   +3 more
doaj   +1 more source

Epitope identification of rabies virus nucleoprotein using immunoinformatics approach

open access: yes
Background Rabies is a deadly and preventable disease. The nucleoprotein of rabies virus has been found to have group-specific antigenic determinants. The rabies virus nucleoprotein can shield dogs and mice from the lethal infection.
Shueb, Mohammad   +7 more
core   +1 more source

A unique nucleoprotein structure associated with the Drosophila melanogaster 18–28 S rDNA nontranscribed spacer

open access: yes, 1986
We have detected unique nucleoprotein particles specific for the 18–28 S rDNA nontranscribed spacer of Drosophilamelanogaster. The particles migrate between di- and trinucleosomes on nucleoprotein gels, and are between mono- and dinucleosomal in DNA ...
Nass, G.Scott   +3 more
core   +1 more source

Pro283 disrupts nucleoprotein α-helical content and is destabilizing relative to other variants at site 283.

open access: yes, 2018
(A) Nucleoprotein crystal structure reveals site 283 is in the center of an α-helix (PDB ID: 2IQH [36]). (B) Molecular dynamics simulations show that Pro283 disrupts nucleoprotein α-helical content compared to Ser283.
Jesse D. Bloom (347889)   +11 more
core   +1 more source

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein

open access: yesFrontiers in Immunology
Complement activation is considered to contribute to the pathogenesis of severe SARS-CoV-2 infection, mainly by generating potent immune effector mechanisms including a strong inflammatory response.
Isabelle Bally   +15 more
doaj   +1 more source

Studies of the formation and transcription of class II promoter-containing ordered nucleoprotein complexes in vitro

open access: yes, 1984
Incubation of supercoiled SV40 DNA with three different HeLa cell free transcription extracts caused the DNA to be converted into ordered nucleoprotein complexes whose physical structure resembled the beads-on-a-string morphology of SV40 ...
Hellwig, Randolph James
core  

SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses

open access: yesMicrobiology Spectrum
Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response.
Ze-zheng Jiang   +9 more
doaj   +1 more source

BRCA2 stabilises RAD51 and DMC1 nucleoprotein filaments through a conserved interaction mode.

open access: yes
BRCA2 is essential for DNA repair by homologous recombination in mitosis and meiosis. It interacts with recombinases RAD51 and DMC1 to facilitate the formation of nucleoprotein filaments on resected DNA ends that catalyse recombination-mediated repair ...

core   +3 more sources

Human immunogenic T cell epitopes in nucleoprotein of human influenza A (H5N1) virus

open access: yes, 2012
1. Two novel HLA-A2.1 specific H5N1 nucleoprotein epitopes(NP373-381 AMDSNTLEL and NP458-466 FQGRGVFEL) capable of activating cytotoxic T-cells in vitro were identified. 2.
Cheng, S. C.S.   +3 more
core  

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