Results 141 to 150 of about 61,031 (268)

Comparative analysis of the conservation of nucleoprotein immunogenic T-cell epitopes of master donor viruses for live and inactivated influenza vaccines

open access: yesИнфекция и иммунитет
Antigen-specific T cells are an important part of antiviral responses, and modern influenza vaccines are designed to induce this mode of immunity. Live attenuated influenza vaccine (LAIV) is a potent inducer of T-cell immunity because of its ability to ...
Alexandra Ya. Rak   +2 more
doaj   +1 more source

Serological Evidence of Schmallenberg Virus Exposure in Ruminant Abortion Cases from Selected Regions of Iran: A Virus Neutralization Test‐Based Study

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Neutralizing antibodies against Schmallenberg virus (SBV) were detected by the virus neutralization test in cattle and sheep with a history of abortion from three selected regions of Iran, providing evidence of prior SBV exposure and highlighting the need for further studies on its epidemiology and circulation.
Mohammad Kiani   +3 more
wiley   +1 more source

Development of a Luciferase Immunosorbent Assay for Detecting Crimean–Congo Hemorrhagic Fever Virus IgG Antibodies Based on Nucleoprotein

open access: yesViruses
Crimean–Congo hemorrhagic fever (CCHF) is a serious tick-borne disease with a wide geographical distribution. Classified as a level 4 biosecurity risk pathogen, CCHF can be transmitted cross-species due to its aerosol infectivity and ability to cause ...
Qi Chen   +3 more
doaj   +1 more source

Photoperiodism‐Specific QTLs Support Switch‐Like Genetic Control of Obligate Long‐Day Photoperiodism in Mimulus guttatus

open access: yesPlant Species Biology, Volume 41, Issue 6, November 2026.
Photoperiodic flowering is well studied in facultative photoperiodism plants, but the genetic basis of obligate photoperiodism remains poorly understood. Using QTL mapping and RNA‐seq in Mimulus guttatus, we identified photoperiodism‐specific QTLs that are distinct from flowering‐time QTLs, supporting switch‐like genetic control of obligate long‐day ...
Po‐Kai Huang, Daniel E. Runcie
wiley   +1 more source

The hnRNP A2B1 is important for the replication of SFTSV and other RNA viruses

open access: yesMicrobiology Spectrum
The heterogeneous nuclear ribonucleoprotein (hnRNP A2B1) is a key component of the hnRNP complex involving RNA modulation in eukaryotic cells and it has also been reported to be involved in the replication of the hepatitis E virus, influenza A virus, and
Xu Zhang   +4 more
doaj   +1 more source

Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic

open access: yesActa Paediatrica, Volume 115, Issue 11, Page 2421-2426, November 2026.
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, Volume 600, Issue 20, Page 3106-3129, October 2026.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, Volume 20, Issue 10, Page 2449-2465, October 2026.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Antigenic site of nucleoprotein gene from Indonesian rabies virus isolate [PDF]

open access: yes, 2019
Background and Aim: Several molecular studies on rabies virus (RABV) have been conducted in Indonesia, but it does not give clear information about molecular characteristics of previous RABV isolate in Indonesia.
Fedik Abdul Rantam, -   +3 more
core  

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