Results 141 to 150 of about 60,064 (253)
Infectious diseases in wild animals have been increasing as a result of their habitat alterations and closer contact with domestic animals. Canine distemper virus (CDV) has been reported in several species of wild carnivores, presenting a threat to ...
Jane Megid +7 more
doaj
Nonlinearities and Switch‐Like Behavior in Gene Expression: From Genetics to Biochemistry and Back
Modest changes in transcription‐factor or chromatin‐regulator dosage can have disproportionate effects when gene‐regulatory systems operate near nonlinear thresholds. Sigmoidal input–output relationships, chromatin and cofactor recruitment, and changes in threshold position or response steepness provide molecular routes by which quantitative dosage ...
Reiner A. Veitia, James A. Birchler
wiley +1 more source
Experiments on Anaphylaxis Part 3. Allergic Reaction of Bovine Thymus Nucleoprotein [PDF]
With the purpose to study the antigenicity of bovine thymus and thymus nucleoprotein the author investigated the passive anaphylaxis in guinea pigs induced by the sera of rabbits immunized with bovine thymus aqueous extract or with bovine thymus ...
Ishikawa, Shuichiro
core
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti +10 more
wiley +1 more source
Herein, we reported the design and synthesis of a novel series of N‐heterocyclic carbene (NHC) complexes originated from the imidazole ring of guanine and guanosine and with different counterions (iodide, acetate, and aminoacidate). The evaluation of the biological activities, that is anticancer and antiviral, indicated L2AuOAc as the best complex ...
Domenico Iacopetta +10 more
wiley +1 more source
Incubation of supercoiled SV40 DNA with three different HeLa cell free transcription extracts caused the DNA to be converted into ordered nucleoprotein complexes whose physical structure resembled the beads-on-a-string morphology of SV40 ...
Hellwig, Randolph James
core
Unravelling the genomic epidemiology and antigenic evolution of Chandipura virus: A genetically constrained neurotropic threat. [PDF]
Kuri PR, Sharma A.
europepmc +1 more source
AXL mediates influenza A virus entry and drives virus-induced inflammation. [PDF]
Zuo W +10 more
europepmc +1 more source
Differences in RNA Binding Between Segmented and Non-Segmented Negative-Strand Virus Nucleocapsids. [PDF]
Ruigrok RWH +4 more
europepmc +1 more source

