Results 11 to 20 of about 47,725 (189)

Autoimmune Effect of Antibodies against the SARS-CoV-2 Nucleoprotein

open access: yesViruses, 2022
COVID-19 caused by SARS-CoV-2 is continuing to spread around the world and drastically affect our daily life. New strains appear, and the severity of the course of the disease itself seems to be decreasing, but even people who have been ill on an ...
Daria Matyushkina   +18 more
doaj   +1 more source

Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus

open access: yesViruses, 2023
The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV),
Katendi Changula   +13 more
doaj   +1 more source

Isolation of Lagos Bat Virus from Water Mongoose

open access: yesEmerging Infectious Diseases, 2006
A genotype 2 lyssavirus, Lagos bat virus (LBV), was isolated from a terrestrial wildlife species (water mongoose) in August 2004 in the Durban area of the KwaZulu-Natal Province of South Africa.
Wanda Markotter   +6 more
doaj   +1 more source

Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging

open access: yesFrontiers in Immunology, 2017
Viruses assemble large macromolecular repeat structures that become part of the infectious particles or virions. Ribonucleocapsids (RNCs) of negative strand RNA viruses are a prime example where repetition of nucleoprotein (NP) along the genome creates a
Tamarand Lee Darling   +3 more
doaj   +1 more source

D471G Mutation in LCMV-NP Affects Its Ability to Self-associate and Results in a Dominant Negative Effect in Viral RNA Synthesis

open access: yesViruses, 2012
Arenaviruses merit significant interest because several family members are etiological agents of severe hemorrhagic fevers, representing a major burden to public health.
Luis Martínez-Sobrido   +3 more
doaj   +1 more source

Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex

open access: yesViruses, 2023
Australian bat lyssavirus (ABLV) shows similar clinical symptoms as rabies, but there are currently no protein structures available for ABLV proteins. In lyssaviruses, the interaction between nucleoprotein (N) and phosphoprotein (N) in the absence of RNA
Camilla M. Donnelly   +4 more
doaj   +1 more source

Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection

open access: yesViruses, 2010
Arenaviruses merit interest both as tractable experimental model systems to study acute and persistent viral infections, and as clinically-important human pathogens. Several arenaviruses cause hemorrhagic fever (HF) disease in humans.
Juan Carlos de la Torre   +2 more
doaj   +1 more source

Truncation of NS1 Protein Enhances T Cell-Mediated Cross-Protection of a Live Attenuated Influenza Vaccine Virus Expressing Wild-Type Nucleoprotein

open access: yesVaccines, 2023
Current seasonal influenza vaccines have suboptimal effectiveness, especially in seasons dominated by viruses that do not match the vaccine. Therefore, finding new approaches to improve the immunogenicity and efficacy of traditional influenza vaccines is
Polina Prokopenko   +8 more
doaj   +1 more source

Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009

open access: yesmSphere, 2018
Influenza A viruses (IAVs) can cause zoonotic infections with pandemic potential when most of the human population is immunologically naive. After a pandemic, IAVs evolve to become seasonal in the human host by acquiring adaptive mutations.
Isabel Pagani   +6 more
doaj   +1 more source

Evolutionary Analysis of a Parrot Bornavirus 2 Detected in a Sulphur-Crested Cockatoo (Cacatua galerita) Suggests a South American Ancestor

open access: yesAnimals, 2023
Parrot bornavirus (PaBV) is an RNA virus that causes Proventricular Dilatation Disease (PDD), neurological disorders, and death in Psittaciformes. Its diversity in South America is poorly known. We examined a Cacatua galerita presenting neuropathies, PDD,
Ruy D. Chacón   +6 more
doaj   +1 more source

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