Results 11 to 20 of about 101,993 (329)

Human Adenovirus Gene Expression and Replication Is Regulated through Dynamic Changes in Nucleoprotein Structure throughout Infection

Viruses, 2023
Human adenovirus (HAdV) is extremely common and can rapidly spread in confined populations such as daycare centers, hospitals, and retirement homes. Although HAdV usually causes only minor illness in otherwise healthy patients, HAdV can cause significant
Morgan R. Jennings, Robin J. Parks
doaj   +1 more source

Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies

Journal of Virology, 2020
In the present study, we have determined SARS-CoV-2-specific antibody responses in sera of acute and postinfection phase subjects. Our results indicate that antibody responses against viral S and N proteins were equally sensitive in the acute phase of ...
C. Fenwick, A. Croxatto, A. Coste, F. Pojer, C. André, C. Pellaton, A. Farina, Jérémy Campos, D. Hacker, K. Lau, B. Bosch, S. Gonseth Nusslé, M. Bochud, V. D'Acremont, D. Trono, Gilbert GREUB, G. Pantaleo   +16 more
semanticscholar   +1 more source

Regulation of Influenza A Virus Nucleoprotein Oligomerization by Phosphorylation [PDF]

Journal of Virology, 2014
Lauren Turrell, Edward Hutchinson, Frank T. Vreede, Ervin Fodor   +3 more
openalex   +2 more sources

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

EMBO Journal, 2020
Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in immunity is not.
S. Caddy, M. Vaysburd, G. Papa, M. Wing, K. O'connell, Diana Stoycheva, Stian Foss, Jan Terje Andersen, A. Oxenius, L. James   +9 more
semanticscholar   +1 more source

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

Viruses, 2020
For highly pathogenic viruses, reporter assays that can be rapidly performed are critically needed to identify potentially functional mutations for further study under maximal containment (e.g., biosafety level 4 [BSL-4]).
Aaron E. Lin, William E. Diehl, Yingyun Cai, Courtney L. Finch, Chidiebere Akusobi, Robert N. Kirchdoerfer, Laura Bollinger, Stephen F. Schaffner, Elizabeth A. Brown, Erica Ollmann Saphire, Kristian G. Andersen, Jens H. Kuhn, Jeremy Luban, Pardis C. Sabeti   +13 more
doaj   +1 more source

A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and Attenuation

Biomolecules, 2022
The basic tenets of the shell disorder model (SDM) as applied to COVID-19 are that the harder outer shell of the virus shell (lower PID—percentage of intrinsic disorder—of the membrane protein M, PIDM) and higher flexibility of the inner shell (higher ...
Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. Uversky   +3 more
doaj   +1 more source

TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Vesicular Stomatitis Virus Infection

Viruses, 2020
Vesicular stomatitis virus (VSV) is a zoonotic, negative-stranded RNA virus of the family Rhabdoviridae. The nucleoprotein (N) of VSV protects the viral genomic RNA and plays an essential role in viral transcription and replication, which makes the ...
G. Patil, Lingling Xu, Yakun Wu, Kun Song, W. Hao, Fang Hua, Lingyan Wang, Shitao Li   +7 more
semanticscholar   +1 more source

Effects of <i>Orthonairovirus hazaraense</i> Nucleoprotein on Gene Expression Profiles in Infected Cells. [PDF]

Viruses
Ohta K, Nishio M.
europepmc   +3 more sources

Nucleoprotein-based nanoscale assembly [PDF]

Proceedings of the National Academy of Sciences, 1997
A system for addressing in the construction of macromolecular assemblies can be based on the biospecificity of DNA (cytosine-5) methyltransferases and the capacity of these enzymes to form abortive covalent complexes at targeted 5-fluorocytosine residues in DNA.
S S, Smith, L, Niu, D J, Baker, J A, Wendel, S E, Kane, D S, Joy   +5 more
openaire   +2 more sources

Development of a Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of SARS-CoV-2 Spike Glycoprotein and Nucleoprotein

Analytical Chemistry, 2020
There is an urgent need for robust and high-throughput methods for SARS-CoV-2 detection in suspected patient samples to facilitate disease management, surveillance, and control.
L. Cazares, Raghothama Chaerkady, Shao Huan Samuel Weng, Chelsea C. Boo, R. Cimbro, Hsiang-En Hsu, Sarav Rajan, W. Dall'acqua, Lori Clarke, K. Ren, P. McTamney, Nicole Kallewaard-LeLay, M. Ghaedi, Y. Ikeda, Sonja Hess   +14 more
semanticscholar   +1 more source