Results 21 to 30 of about 60,064 (253)

Functional domains of the influenza A virus PB2 protein:identification of NP- and PB1-binding sites [PDF]

, 2004
Influenza virus genomic RNA segments are packaged into ribonucleoprotein (RNP) structures by the PB1, PB2, and PA subunits of an RNA polymerase and a single-strand RNA-binding nucleoprotein (NP).
Poole, Emma, Digard, Paul, Medcalf, Liz, Elton, Debra, Poole, Emma L   +4 more
core   +1 more source

Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging

Frontiers in Immunology, 2017
Viruses assemble large macromolecular repeat structures that become part of the infectious particles or virions. Ribonucleocapsids (RNCs) of negative strand RNA viruses are a prime example where repetition of nucleoprotein (NP) along the genome creates a
Tamarand Lee Darling, Tamarand Lee Darling, Laura Jo Sherwood, Andrew Hayhurst   +3 more
doaj   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Dubuquoy, Catherine, C., Eléouët, Jean-François, Soulestin, Marion, Deville, Sébastien, Durand, Guillaume, Meyer, Gilles, G., Bernard, Julie, Bernadet, Philippe, Bernardet, Philippe, Petit-Camurdan, Agnès, Schwartz-Cornil, Isabelle, Riffault, Sabine, Dubosclard, Virginie, Eleouet, Jean Francois, J. F., Meyer, Gilles, Castagné, Nathalie, Deplanche, Martine, Bernex, Florence, Dubuquoy, Catherine   +18 more
core   +1 more source

Potential antiviral peptides against the nucleoprotein of SARS-CoV-2

, 2022
Nucleoprotein is a conserved structural protein of SARS-CoV-2, which is involved in several functions, including replication, packaging, and transcription.
Kaium, Md Abdul, Mahdi, Iktedar, Halim, Mohammad A., Ali, Md. Ackas, Sufian, Md. Abu, Badhan, Raina Masnoon, Yeasmin, Humyara, Ali, Md Ackas, Kaium, Md. Abdul, Sufian, Md Abu, Hossain, Imtiaz, Islam, Rajib   +11 more
core   +1 more source

D471G Mutation in LCMV-NP Affects Its Ability to Self-associate and Results in a Dominant Negative Effect in Viral RNA Synthesis

Viruses, 2012
Arenaviruses merit significant interest because several family members are etiological agents of severe hemorrhagic fevers, representing a major burden to public health.
Luis Martínez-Sobrido, Juan C. de la Torre, Benson Y.H. Cheng, Emilio Ortiz-Riaño   +3 more
doaj   +1 more source

Structure of the hDmc1-ssDNA filament reveals the principles of its architecture [PDF]

, 2010
In eukaryotes, meiotic recombination is a major source of genetic diversity, but its defects in humans lead to abnormalities such as Down's, Klinefelter's and other syndromes.
Dmitry V Bugreev, Julie Hodgkinson, Yuriy L Chaban, Bugreev, DV, Orlova, Elena, Orlova, EV, Hodgkinson, J.L., Orlova Elena V., Chaban, Y.L., Bugreev, D.V., Andrei L Okorokov, Chaban Yuriy L., Okorokov, AL, Elena V Orlova, Okorokov, A.L., Hodgkinson, J, Bugreev Dmitry V., Chaban, YL, Okorokov Andrei L., Mazin, AV, Hodgkinson Julie, Mazin, A.V., Alexander V Mazin, Mazin Alexander V.   +23 more
core   +2 more sources

Nucleoprotein structure of adenovirus [PDF]

The structure of the nucleoprotein core of adenovirus has been investigated. Using a combination of biophysical techniques and nuclease digestion I have determined that the adenovirus core, as isolated with pyridine, shares several physical properties ...
Corden, Jeffry Lynn
core   +6 more sources

Phosphorylation sites within Ebola virus nucleoprotein [PDF]

, 2015
To understand the infection process, the viral multiplication and entry to the cell is widely studied. The Ebola virus nucleoprotein is the important problem for the pathological process.
Sora Yasri, Yasri, Sora, Viroj Wiwanitkit, Wiwanitkit, Viroj   +3 more
core   +1 more source

Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection

Viruses, 2010
Arenaviruses merit interest both as tractable experimental model systems to study acute and persistent viral infections, and as clinically-important human pathogens. Several arenaviruses cause hemorrhagic fever (HF) disease in humans.
Juan Carlos de la Torre, Luis Martínez-Sobrido, Persephone Borrow   +2 more
doaj   +1 more source

Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex

Viruses, 2023
Australian bat lyssavirus (ABLV) shows similar clinical symptoms as rabies, but there are currently no protein structures available for ABLV proteins. In lyssaviruses, the interaction between nucleoprotein (N) and phosphoprotein (N) in the absence of RNA
Camilla M. Donnelly, Murray Stewart, Justin A. Roby, Vinod Sundaramoorthy, Jade K. Forwood   +4 more
doaj   +1 more source