Monomeric Nucleoprotein of Influenza A Virus [PDF]
PLoS Pathogens, 2013 Isolated influenza A virus nucleoprotein exists in an equilibrium between monomers and trimers. Samples containing only monomers or only trimers can be stabilized by respectively low and high salt. The trimers bind RNA with high affinity but remain trimmers, whereas the monomers polymerise onto RNA forming nucleoprotein-RNA complexes.
Chenavas, Sylvie +8 more
openaire +10 more sources
Observation of arenavirus nucleoprotein heptamer assembly [PDF]
, 2021 International audienceArenaviruses are enveloped viruses containing a segmented, negative and ambisense single‐stranded RNA genome wrapped with a nucleoprotein.
Awa Diop +14 more
core +1 more source
Endogenous Bornavirus-Like Nucleoprotein 1 Regulates Cellular Processes and DNA Double-Strand Breaks in U-87 MG Glioblastoma Cells. [PDF]
Cancer Rep (Hoboken)ABSTRACT Background Glioblastoma (GBM) is a common brain cancer with a poor prognosis and a high recurrence rate. DNA damage repair plays a crucial role in GBM carcinogenesis and treatment resistance. Human endogenous bornavirus‐like nucleoprotein 1 (EBLN1) regulates cellular processes and genetic stability. However, the biological role of EBLN1 in GBM
Liang J +6 more
europepmc +2 more sources
Structural and functional studies of novel mechanisms of Lassa fever virus nucleoprotein in immune suppression, viral RNA transcription and replication [PDF]
, 2013 Lassa fever virus is one of the most dangerous viruses of arenaviridae family, causing more than 500,000 infections per year in Africa. The fatality rate for hospitalized patients is as high as 20%.
Qi, Xiaoxuan
core +2 more sources
Architecture of a Polycomb Nucleoprotein Complex [PDF]
Molecular Cell, 2006 Polycomb group (PcG) epigenetic silencing proteins act through cis-acting DNA sequences, named Polycomb response elements (PREs). Within PREs, Pleiohomeotic (PHO) binding sites and juxtaposed Pc binding elements (PBEs) function as an integrated DNA platform for the synergistic binding of PHO and the multisubunit Polycomb core complex (PCC).
Tielenius Kruythoff-Mohd Sarip, Adone +5 more
openaire +3 more sources
Structure of schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation [PDF]
, 2013 Schmallenberg virus (SBV), a newly emerged orthobunyavirus (family <i>Bunyaviridae</i>), has spread rapidly across Europe and has caused congenital abnormalities in the offspring of cattle, sheep, and goats.
Li, P. +8 more
core +1 more source
Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus
Viruses, 2023 The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV),
Katendi Changula +13 more
doaj +1 more source
Radiation damage to nucleoprotein complexes in macromolecular crystallography [PDF]
, 2015 Significant progress has been made in macromolecular crystallography over recent years in both the understanding and mitigation of X-ray induced radiation damage when collecting diffraction data from crystalline proteins.
Ravelli, Raimond B. G. +8 more
core +1 more source
Isolation of Lagos Bat Virus from Water Mongoose
Emerging Infectious Diseases, 2006 A genotype 2 lyssavirus, Lagos bat virus (LBV), was isolated from a terrestrial wildlife species (water mongoose) in August 2004 in the Durban area of the KwaZulu-Natal Province of South Africa.
Wanda Markotter +6 more
doaj +1 more source
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott +16 more
core +1 more source