Results 31 to 40 of about 47,725 (189)

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Comparative analysis of the conservation of nucleoprotein immunogenic T-cell epitopes of master donor viruses for live and inactivated influenza vaccines

Инфекция и иммунитет
Antigen-specific T cells are an important part of antiviral responses, and modern influenza vaccines are designed to induce this mode of immunity. Live attenuated influenza vaccine (LAIV) is a potent inducer of T-cell immunity because of its ability to ...
Alexandra Ya. Rak, L. G. Rudenkо, I. N. Isakova-Sivak   +2 more
doaj   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Development of a Luciferase Immunosorbent Assay for Detecting Crimean–Congo Hemorrhagic Fever Virus IgG Antibodies Based on Nucleoprotein

Viruses
Crimean–Congo hemorrhagic fever (CCHF) is a serious tick-borne disease with a wide geographical distribution. Classified as a level 4 biosecurity risk pathogen, CCHF can be transmitted cross-species due to its aerosol infectivity and ability to cause ...
Qi Chen, Yuting Fang, Ning Zhang, Chengsong Wan   +3 more
doaj   +1 more source

Cartooning in Biological Learning

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Teaching bioscience subjects requires helping students understand complicated and abstract concepts. An effective method of helping students understand these abstract topics is the use of concept cartoons. Concept cartoons are cartoon‐style drawings that illustrate everyday situations. In constructivism, learners create their own knowledge and
Soukaina Bahsoun, Mhairi Morris, Elizabeth Akam   +2 more
wiley   +1 more source

The hnRNP A2B1 is important for the replication of SFTSV and other RNA viruses

Microbiology Spectrum
The heterogeneous nuclear ribonucleoprotein (hnRNP A2B1) is a key component of the hnRNP complex involving RNA modulation in eukaryotic cells and it has also been reported to be involved in the replication of the hepatitis E virus, influenza A virus, and
Xu Zhang, Li-na Yan, Bin-yan Liu, Chuan-min Zhou, Xue-jie Yu   +4 more
doaj   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

Equine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock, John Grewar, Richard Newton   +2 more
wiley   +1 more source

Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests

Cell Reports Medicine, 2021
Summary: The ongoing coronavirus disease 2019 (COVID-19) pandemic is a major global public health concern. Although rapid point-of-care testing for detecting viral antigen is important for management of the outbreak, the current antigen tests are less ...
Yutaro Yamaoka, Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Rikako Funabashi, Koji Okudela, Sayaka Kikuchi, Junichi Katada, Atsuhiko Wada, Toshiki Takei, Mayuko Nishi, Kohei Shimizu, Hiroki Ozawa, Shuzo Usuku, Chiharu Kawakami, Nobuko Tanaka, Takeshi Morita, Hiroyuki Hayashi, Hideaki Mitsui, Keita Suzuki, Daisuke Aizawa, Yukihiro Yoshimura, Tomoyuki Miyazaki, Etsuko Yamazaki, Tadaki Suzuki, Hirokazu Kimura, Hideaki Shimizu, Nobuhiko Okabe, Hideki Hasegawa, Akihide Ryo   +28 more
doaj   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Inhibition of influenza virus infection by garlic oil and juice in cell culture

JSFA reports, EarlyView.
Abstract Background Influenza virus infections are a significant global health and economic burden. Garlic (Allium sativum) has been proposed to have antimicrobial properties. Raw garlic consumption has been widely advocated on the internet to fight influenza by many public health agencies, information of which is easily accessible by the public. There
Carla Breen, Timothy Smith, Nick Diamantopoulos, Julie McAuley   +3 more
wiley   +1 more source