Results 81 to 90 of about 48,568 (203)

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 3000-3024, August 2026.
This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong, Zhanchun Wang, Dingzhong Tang, Wei Wang   +3 more
wiley   +1 more source

Telomere Length at Recruitment Predicts Lifespan and Lifetime Reproductive Success in the Barn Swallow (Hirundo rustica)

Molecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT Identifying molecular mechanisms linked to variation in lifespan, reproductive output and sexually selected traits is key to understanding life‐history evolution in wild populations. Telomere length (TL) and attrition (ΔTL) have been proposed as biomarkers of somatic state and maintenance (survival).
Andrea Novelli, Manuela Caprioli, Roberto Ambrosini, Alessandra Costanzo, Diego Rubolini, Marco Parolini, Andrea Romano   +6 more
wiley   +1 more source

To be or not to be phosphorylated: understanding the role of Ebola virus nucleoprotein in the dynamic interplay with the transcriptional activator VP30 and the host phosphatase PP2A-B56

Emerging Microbes and Infections
Ebola virus (EBOV) transcription is essentially regulated via dynamic dephosphorylation of its viral transcription activator VP30 by the host phosphatase PP2A.
Lennart Kämper, Ida Kuhl, Melina Vallbracht, Thomas Hoenen, Uwe Linne, Axel Weber, Petr Chlanda, Michael Kracht, Nadine Biedenkopf   +8 more
doaj   +1 more source

Crimean‐Congo Haemorrhagic Fever Virus Exposure in Horses and Donkeys in Border Livestock Markets of Nigeria

Zoonoses and Public Health, Volume 73, Issue 5, Page 422-430, August 2026.
ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
David O. Ehizibolo, Olumuyiwa Oyekan, Nicodemus Mkpuma, Habibu Haliru, Ibrahim Garba, Isa Z. Turaki, Samdi Kennedy, Joshua M. Shallangwa, Caleb S. Kilyobas, Abdullahi Mohammed, Musa A. Muhammad, Mansur Abubakar, Maryam Muhammad, Corrie Brown, Bonto Faburay   +14 more
wiley   +1 more source

Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization

Frontiers in Immunology
IntroductionThere is an urgent need for influenza vaccine strategies that enhance protection against influenza virus drift and across different subtypes. The conserved viral nucleoprotein (NP) is the most abundant viral protein during replication, and a
Ebony N. Gary, Abigail R. Trachtman, Dan Wang, Suman Bharti, Ying Ye, Nicholas J. Tursi, Nicholas J. Tursi, Martina Tomirotti, Martina Tomirotti, Jillian Eisenhauer, Jillian Eisenhauer, Jacqueline D. Chu, David Custodio Zegarra, Casey E. Hojecki, Micki Zheng, Micki Zheng, Jayamanna Wickramasinghe, David B. Weiner, Ami Patel   +18 more
doaj   +1 more source

Therapeutic intervention with sinomenine and irisin to preserve cardiac function after ischaemia–reperfusion injury

Experimental Physiology, Volume 111, Issue 8, Page 3557-3569, 1 August 2026.
Abstract Despite advancements in reperfusion therapy, myocardial ischaemia–reperfusion (IR) injury remains a major clinical challenge. This study investigated whether a novel dual‐target pre‐conditioning strategy using sinomenine and irisin could enhance myocardial resistance against IR injury. Ninety male Sprague–Dawley rats were utilized.
Lianjun Wu, Sining Bi, Amany Belal, Zhuzhu Liu   +3 more
wiley   +1 more source

MiR-130c-5p targets the SHVV n gene and upregulates immune cytokines (IL-6, IL-22, IL-1β) to inhibit viral replication

Frontiers in Immunology
BackgroundSnakehead vesiculovirus (SHVV) has led to huge economic losses in snakehead aquaculture, and its pathogenic mechanisms is still not fully understood.
Jin Wei, Yan Ji, Yaqian Bai, Rui Cheng, Jiaqi Zhang, Xianqin Hu, Chi Zhang   +6 more
doaj   +1 more source

Development of a Trivalent Seasonal Influenza Vaccine Using Long α‐Helix‐Mediated Trimeric HA1 Proteins Produced in Baculovirus‐Insect Cell System

MedComm, Volume 7, Issue 8, August 2026.
Ning Guo, Zhibin Xu, Xinyu Chen, Xiaonan Han, Ting Xue, Jinghua Yan, Qingrui Huang   +6 more
wiley   +1 more source

Nucleoproteins of Cell Nuclei [PDF]

Proceedings of the National Academy of Sciences, 1942
A E, Mirsky, A W, Pollister
openaire   +2 more sources

Study on the immune enhancers against Micropterus salmoides rhabdovirus infection

Journal of Limnology
Micropterus salmoides rhabdovirus (MSRV) is one of the most serious pathogens harming M. salmoides juvenile, which had brought huge economic losses to farming industry. Studies involving candidate genes to the clinical diseases, however, are limited. In
Ning Lei, Chaonan Zhang, Yanchao Wang, Junjie Zhu   +3 more
doaj   +1 more source