Results 71 to 80 of about 55,866 (243)

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation

Journal of Integrative Plant Biology, EarlyView.
This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong, Zhanchun Wang, Dingzhong Tang, Wei Wang   +3 more
wiley   +1 more source

Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8+ T cells more relevant to current infections

Human Vaccines & Immunotherapeutics, 2018
Live attenuated influenza vaccines (LAIV) induce CD8+ T lymphocyte responses that play an important role in killing virus-infected cells. Despite the relative conservation of internal influenza A proteins, the epitopes recognized by T cells can undergo ...
D. Korenkov, T. H. O. Nguyen, I. Isakova-Sivak, T. Smolonogina, L. E. Brown, K. Kedzierska, L. Rudenko   +6 more
doaj   +1 more source

Modulation of nuclear localization of the influenza virus nucleoprotein through interaction with actin filaments

, 1999
The influenza virus genome is transcribed in the nuclei of infected cells but assembled into progeny virions in the cytoplasm. This is reflected in the cellular distribution of the virus nucleoprotein (NP), a protein which encapsidates genomic RNA to ...
Pope, Brian, Digard, Paul, Medcalf, Liz, Weeds, Alan, Elton, Debra, Bishop, Konrad   +5 more
core  

Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs. [PDF]

, 2017
Studies in the mouse model indicate that the nucleoprotein of influenza A virus represents an interesting vaccine antigen being well conserved across subtypes of influenza virus but still able to induce protective immune responses.
Python, Sylvie, Vielle, Nathalie Jane, Nathalie J. Vielle, Gert Zimmer, Zumkehr, Béatrice, Summerfield, Artur, Sylvie Python, Horst Posthaus, Zimmer, Gert, Ruggli, Nicolas, Daniel Brechbühl, Beatrice Zumkehr, Artur Summerfield, Ricklin, Meret, Posthaus, Horst, Meret E. Ricklin, Nicolas Ruggli, Brechbühl, Daniel   +17 more
core   +1 more source

Crimean‐Congo Haemorrhagic Fever Virus Exposure in Horses and Donkeys in Border Livestock Markets of Nigeria

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
David O. Ehizibolo, Olumuyiwa Oyekan, Nicodemus Mkpuma, Habibu Haliru, Ibrahim Garba, Isa Z. Turaki, Samdi Kennedy, Joshua M. Shallangwa, Caleb S. Kilyobas, Abdullahi Mohammed, Musa A. Muhammad, Mansur Abubakar, Maryam Muhammad, Corrie Brown, Bonto Faburay   +14 more
wiley   +1 more source

Identification of lurasidone as a potent inhibitor of severe fever with thrombocytopenia syndrome virus by targeting the viral nucleoprotein

Frontiers in Microbiology
IntroductionSevere fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes acute febrile illness with thrombocytopenia and a high mortality rate in humans.
Ting Cheng, Qingcui Xiao, Jing Cui, Shuangjie Dong, Yuqin Wu, Wenqiang Li, Xinya Yang, Lina Ma, Zhiyong Li, Zhiyong Li, Zhiyong Li, Peng Sun, Peng Sun, Peng Sun, Yinli Xie, Yinli Xie   +15 more
doaj   +1 more source

Experiments on Anaphylaxis Part 2. The Antigenicity of Bovine Thymus Nucleoprotein [PDF]

, 1959
By means of complement fixation test the author conducted a comparative study on the reactivity of the serum of the rabbit immunized with bovine thymus nucleoprotein on different visceral extracts of bovine and swine, and obtained the following results ...
Ishikawa, Shuichiro
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, Volume 16, Issue 6, Page 1213-1221, June 2026.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Dimerization of Rabies Virus Phosphoprotein and Phosphorylation of Its Nucleoprotein Enhance Their Binding Affinity

Viruses
The dynamic interplay between a multimeric phosphoprotein (P) and polymeric nucleoprotein (N) in complex with the viral RNA is at the heart of the functioning of the RNA-synthesizing machine of negative-sense RNA viruses of the order Mononegavirales.
Euripedes de Almeida Ribeiro, Cédric Leyrat, Francine C. A. Gérard, Marc Jamin   +3 more
doaj   +1 more source

Über ein aus menschlichen und tierischen Geweben isoliertes Nucleoprotein mit Kollagen-fällenden Eigenschaften. V. Über ein Nucleoprotein aus Streptokokken der Gruppe A und C, Hautreaktionen bei rheumatischem Fieber und Autoaggressions-Krankheiten mit Nucleoprotein aus Streptokokken und menschlichen Geweben

, 1966
In weiteren Versuchen wurden Streptokokken der Gruppe A und C dem in der I. Mitteilung beschriebenen Trennungsgang unterworfen. Es gelang dabei, aus diesen Streptokokken ein Nucleoprotein zu isolieren, das in bezug auf seine elektrophoretischen ...
Wilhelm, G.
core   +1 more source