Results 71 to 80 of about 81,602 (239)

Dolphin Morbillivirus Associated with a Mass Stranding of Sperm Whales, Italy [PDF]

, 2017
In September 2014, 7 sperm whales stranded along the Adriatic Italian coastlines. Postmortem investigations on 3 dead females dead and in 1 fetus harbored by the largest one revealed molecular and immunoistochemical evidences of dolphin morbillivirus ...
Cardeti, Giusy, Casalone, Cristina, CENTELLEGHE, CINZIA, Cersini, Antonella, Di Guardo, Giovanni, Fichi, Gianluca, Francesco, Cristina Esmeralda Di, MAZZARIOL, SANDRO, Mignone, Walter, Petrella, Antonio, Provvido, Andrea Di, Renzo, Ludovica Di   +11 more
core   +2 more sources

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests

Cell Reports Medicine, 2021
Summary: The ongoing coronavirus disease 2019 (COVID-19) pandemic is a major global public health concern. Although rapid point-of-care testing for detecting viral antigen is important for management of the outbreak, the current antigen tests are less ...
Yutaro Yamaoka, Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Rikako Funabashi, Koji Okudela, Sayaka Kikuchi, Junichi Katada, Atsuhiko Wada, Toshiki Takei, Mayuko Nishi, Kohei Shimizu, Hiroki Ozawa, Shuzo Usuku, Chiharu Kawakami, Nobuko Tanaka, Takeshi Morita, Hiroyuki Hayashi, Hideaki Mitsui, Keita Suzuki, Daisuke Aizawa, Yukihiro Yoshimura, Tomoyuki Miyazaki, Etsuko Yamazaki, Tadaki Suzuki, Hirokazu Kimura, Hideaki Shimizu, Nobuhiko Okabe, Hideki Hasegawa, Akihide Ryo   +28 more
doaj   +1 more source

Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function [PDF]

, 2017
No abstract ...
Smith, Brian O., Spies, Maria
core   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Antiviral and antioxidant activity of a hydroalcoholic extract from Humulus lupulus L. [PDF]

, 2018
A hydroalcoholic extract from female inflorescences of Humulus lupulus L. (HOP extract) was evaluated for its anti-influenza activity. The ability of the extract to interfere with different phases of viral replication was assessed, as well as its effect ...
Carissimi, Stefania, Celestino, Ignacio, Checconi, Paola, DE ANGELIS, Marta, DI GIACOMO, Silvia, DI SOTTO, Antonella, Limongi, Dolores, Locatelli, Marcello, Martinoli, Lucia, Nencioni, Lucia, Palamara, ANNA TERESA, Rossi, Valeria, Toniolo, Chiara   +12 more
core   +1 more source

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

New Plant Protection, EarlyView.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

The Hong Kong Influenza Virus: Treats to the Portrait after 50 Years and the Future Influenza Pandemic

Эпидемиология и вакцинопрофилактика, 2020
Relevance. Of the different subtypes, H3N2 influenza virus subtype has the highest variability and pathogenicity, often dominates in epidemiological seasons and induces high mortality exceeding its rate in pandemic.
E. P. Kharchenko
doaj   +1 more source

Genome encapsidation by orthobunyavirus nucleoproteins [PDF]

Proceedings of the National Academy of Sciences, 2013
All negative-sense, single-stranded RNA (−ssRNA) viruses encode a nucleoprotein (NP), the major function of which is to bind viral RNAs and encapsidate them as ribonucleoprotein complexes (RNPs) (1, 2). Consequently, the genomes of −ssRNA viruses do not exist as naked RNA but rather as protein–RNA complexes with high-order structures. In PNAS, Li et al.
Wenjie, Zheng, Yizhi Jane, Tao
openaire   +2 more sources

Context-Dependent Remodeling of Rad51–DNA Complexes by Srs2 Is Mediated by a Specific Protein–Protein Interaction [PDF]

, 2014
The yeast Srs2 helicase removes Rad51 nucleoprotein filaments from single-stranded DNA (ssDNA), preventing DNA strand invasion and exchange by homologous recombination.
Antony, Edwin, Lytle, Anna K., Myong, Sua, Origanti, Sofia S., Qiu, Yupeng, VonGermeten, Jeffrey   +5 more
core   +1 more source