Results 181 to 190 of about 339,632 (390)

SOME CHEMICAL PROPERTIES OF DESOXYRIBOSE NUCLEOSIDES

open access: hybrid, 1951
Lionel A. Manson, J. O. Lampen
openalex   +1 more source

Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro

open access: yesChemistryEurope, EarlyView.
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling   +5 more
wiley   +1 more source

SYNTHETIC NUCLEOSIDES

open access: hybrid, 1925
P.A. Levene, Harry Sobotka
openalex   +1 more source

Milligram‐Scale Enzymatic Synthesis of Base‐Modified DNA through Primer Extension: Polymerase Synthesis and NMR Structures of DNA Containing Phenyl‐Substituted Nucleobases

open access: yesChemistryEurope, EarlyView.
Larger‐scale enzymatic synthesis of base‐modified DNA is developed using primer extension with KOD(exo‐) DNA polymerase allowing preparation of milligram amounts of the modified DNA sufficient for NMR structural analysis. Milligram (≈200 nmol) scale enzymatic synthesis of base‐modified DNA is developed based on primer extension using easily accessible ...
Veronika Raindlová   +6 more
wiley   +1 more source

Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease

open access: yesMicrobiology Spectrum
Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak.
Rajini R. Mudhasani   +17 more
doaj   +1 more source

Steric and Geometric Tuning of π‐Conjugated Antennae in Europium(III) Complexes for Selective ADP Recognition

open access: yesChemistry – A European Journal, EarlyView.
We present four new macrocyclic Eu(III) complexes and demonstrate how ligand structure and positional tuning of π‐conjugated antennae modulate steric demand and anion binding site geometry. This enables size and shape complementarity for selective ADP recognition in water over competing phosphoanions.
Samantha E. Bodman, Stephen J. Butler
wiley   +1 more source

Efficacy of DNA Intercalator‐Conjugated Triplex‐Forming Oligonucleotide as Anticancer Agent

open access: yesChemMedChem, Accepted Article.
A triplex‐forming oligonucleotide (TFO) can form a sequence‐specific triple helix via Hoogsteen hydrogen bonding to polypurine tracts within a major groove side of a DNA duplex. Triplex formation can induce a double‐strand break, and this phenomenon at the amplified gene loci can selectively induce the cell death of cancer cells with specific gene ...
Haruki Toyama   +5 more
wiley   +1 more source

DEGRADATION OF SUBSTITUTED PYRIMIDINE NUCLEOSIDES BY ESCHERICHIA COLI AND BACILLUS SUBTILIS

open access: hybrid, 1954
Irving J. Slotnick   +2 more
openalex   +1 more source

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