Results 181 to 190 of about 339,632 (390)
SOME CHEMICAL PROPERTIES OF DESOXYRIBOSE NUCLEOSIDES
Lionel A. Manson, J. O. Lampen
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Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling+5 more
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Effect of nucleoside triphosphate and magnesium ion concentration on the stability and function of rat liver polysomes in vitro [PDF]
Andrzej Prończuk+2 more
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Larger‐scale enzymatic synthesis of base‐modified DNA is developed using primer extension with KOD(exo‐) DNA polymerase allowing preparation of milligram amounts of the modified DNA sufficient for NMR structural analysis. Milligram (≈200 nmol) scale enzymatic synthesis of base‐modified DNA is developed based on primer extension using easily accessible ...
Veronika Raindlová+6 more
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Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease
Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak.
Rajini R. Mudhasani+17 more
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We present four new macrocyclic Eu(III) complexes and demonstrate how ligand structure and positional tuning of π‐conjugated antennae modulate steric demand and anion binding site geometry. This enables size and shape complementarity for selective ADP recognition in water over competing phosphoanions.
Samantha E. Bodman, Stephen J. Butler
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Efficacy of DNA Intercalator‐Conjugated Triplex‐Forming Oligonucleotide as Anticancer Agent
A triplex‐forming oligonucleotide (TFO) can form a sequence‐specific triple helix via Hoogsteen hydrogen bonding to polypurine tracts within a major groove side of a DNA duplex. Triplex formation can induce a double‐strand break, and this phenomenon at the amplified gene loci can selectively induce the cell death of cancer cells with specific gene ...
Haruki Toyama+5 more
wiley +1 more source
DEGRADATION OF SUBSTITUTED PYRIMIDINE NUCLEOSIDES BY ESCHERICHIA COLI AND BACILLUS SUBTILIS
Irving J. Slotnick+2 more
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