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PYRIMIDINETHIONE NUCLEOSIDES AND THEIR DEAZA ANALOGUES
Nucleosides, Nucleotides and Nucleic Acids, 2002The methods of preparation, structure, chemical properties and synthetic potentiality of pyrimidinethione nucleosides and their deaza analogues are reported.
Galal H, Elgemeie, Eman A, Kamal
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Hospital practice (Office ed.), 1992
At present, the nucleoside analogues are the cornerstone of therapy for HIV infection. Of the three that have been approved for clinical use, AZT is the only one that has clearly proved to prolong survival. ddI is indicated for patients who develop toxicity or resistance to AZT. Current data do not support ddC monotherapy as first-line treatment.
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At present, the nucleoside analogues are the cornerstone of therapy for HIV infection. Of the three that have been approved for clinical use, AZT is the only one that has clearly proved to prolong survival. ddI is indicated for patients who develop toxicity or resistance to AZT. Current data do not support ddC monotherapy as first-line treatment.
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Nucleoside Analogues Exerting Antiviral Activity Through a Non‐Nucleoside Mechanism.
ChemInform, 2004In analogy with maribavir [1-(beta-L-ribofuranosyl)-isopropylamino-5,6-dichlorobenzimidazole], a nucleoside analogue that acts against human cytomegalovirus (HCMV) by a non-nucleoside mechanism, here I present three other examples of classes of nucleoside analogues (i.e.
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Hospital practice (Office ed.), 1992
Combination antiretroviral therapy is an important development in the management of HIV infection. AZT with ddC is the first such combination to be approved for clinical use. Several issues remain, however, including the precise clinical benefit and toxicity of combination therapy, its effect on drug resistance, and the development of ever more ...
G X, McLeod, S M, Hammer
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Combination antiretroviral therapy is an important development in the management of HIV infection. AZT with ddC is the first such combination to be approved for clinical use. Several issues remain, however, including the precise clinical benefit and toxicity of combination therapy, its effect on drug resistance, and the development of ever more ...
G X, McLeod, S M, Hammer
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Hospital practice (Office ed.), 1992
The three approved nucleoside analogues are fairly well tolerated, and only a few patients have to discontinue therapy permanently. However, because clinical experience is limited, especially with ddI and ddC, delayed toxicities are likely to emerge over time.
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The three approved nucleoside analogues are fairly well tolerated, and only a few patients have to discontinue therapy permanently. However, because clinical experience is limited, especially with ddI and ddC, delayed toxicities are likely to emerge over time.
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Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues
Chemical Society Reviews, 2021Dmytro Dziuba +2 more
exaly
Analogues of nucleoside polyphosphates
Journal of Molecular Biology, 1970Pierre Remy +4 more
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Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases
Nature Reviews Drug Discovery, 2013David Durantel +2 more
exaly