Results 101 to 110 of about 141,257 (371)
Quantitative MNase-seq accurately maps nucleosome occupancy levels
Genome Biology, 2019 Micrococcal nuclease (MNase) is widely used to map nucleosomes. However, its aggressive endo-/exo-nuclease activities make MNase-seq unreliable for determining nucleosome occupancies, because cleavages within linker regions produce oligo- and mono ...
Răzvan V. Chereji +2 more
semanticscholar +1 more source
The Nucleosome Remodeling Factor [PDF]
FEBS Letters, 2011 An essential component of the chromatin remodeling machinery is NURF (Nucleosome Remodeling Factor), the founding member of the ISWI family of chromatin remodeling complexes. In vertebrates and invertebrates alike, NURF has many important functions in chromatin biology including regulating transcription, establishing boundary elements, and promoting ...
Joseph W. Landry, Suehyb G. Alkhatib
openaire +3 more sources
Advanced Science, EarlyView.In Arabidopsis, the homeostasis of full‐ and hemi‐methylation is mainly regulated by maintenance methylation. The maintenance methylation at hemi‐methylated dyads is highly efficient but the efficiency differs at euchromatic or heterochromatic regions. Nucleosomes impair the hemi‐ to full‐methylation transition. Lagged methylation maintenance after DNA
Hengye Chen, Chenhuan Xu
wiley +1 more source
In vivo effects of histone H3 depletion on nucleosome occupancy and position in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2012 Previous studies in Saccharomyces cerevisiae established that depletion of histone H4 results in the genome-wide transcriptional de-repression of hundreds of genes.
Andrea J Gossett, Jason D Lieb
doaj +1 more source
Nucleosome Positioning with Set of Key Positions and Nucleosome Affinity [PDF]
The Open Biomedical Engineering Journal, 2014 The formation and precise positioning of nucleosome in chromatin occupies a very important role in studying life process. Today, there are many researchers who discovered that the positioning where the location of a DNA sequence fragment wraps around a histone octamer in genome is not random but regular.
Jia Wang, Shuai Liu, Weina Fu
openaire +3 more sources
Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping [PDF]
, 2012 We have mapped sequence-directed nucleosome positioning on genomic DNA molecules using high-throughput sequencing. Chromatins, prepared by reconstitution with either chicken or frog histones, were separately digested to mononucleosomes using either ...
Allan, James +3 more
core +3 more sources
Advanced Science, EarlyView.High‐resolution spatiotemporal transcriptomic data from male and female spinach inflorescences across four key stages first reveal the sex differentiation initiates at the four‐leaf stage and is governed by epigenetic regulation via the SpMSI1‐SpHDT2 complex.
Chen You +10 more
wiley +1 more source
Nucleosome-mediated cooperativity between transcription factors [PDF]
, 2009 Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes.
Adams +49 more
core +4 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source
Transcriptional interaction-assisted identification of dynamic nucleosome positioning
BMC Bioinformatics, 2009 Background Nucleosomes regulate DNA accessibility and therefore play a central role in transcription control. Computational methods have been developed to predict static nucleosome positions from DNA sequences, but nucleosomes are dynamic in vivo ...
Deng Yangyang +6 more
doaj +1 more source