Results 131 to 140 of about 64,059 (299)
Divalent Metal- and High Mobility Group N Protein-Dependent Nucleosome Stability and Conformation
High mobility group N proteins (HMGNs) bind specifically to the nucleosome core and act as chromatin unfolding and activating factors. Using an all-Xenopus system, we found that HMGN1 and HMGN2 binding to nucleosomes results in distinct ion-dependent ...
Michelle S. Ong+2 more
doaj +1 more source
Abstract Transmembrane alkane monooxygenase (AlkB)‐type monooxygenases, especially AlkB2 monooxygenases, are crucial for aerobic degradation of the medium‐to‐long‐chain n‐alkanes in hydrocarbon‐utilizing microorganisms. In this study, we identified a GntR/VanR transcription regulator AlkR of Pseudomonas aeruginosa SJTD‐1 involved in the negative ...
Wanli Peng+11 more
wiley +1 more source
Gene splice sites correlate with nucleosome positions [PDF]
Gene sequences in the vicinity of splice sites are found to possess dinucleotide periodicities, especially RR and YY, with the period close to the pitch of nucleosome DNA. This confirms previously reported finding about preferential positioning of splice junctions within the nucleosomes.
arxiv
Structural Aspects of Histone Complexes and Nucleosomes Revealed by the Accessibility of Cysteine Side Chains [PDF]
Jürgen Bode, Ulrich-Dieter Standt
openalex +1 more source
Abstract Objective Thermogenic beige adipocytes emerge in white adipose tissue (WAT) under certain physiological and pathological conditions, leading to increased energy expenditure, insulin sensitivity, and glucose tolerance. The induction of beige adipocyte formation represents a promising therapeutic approach for obesity and associated chronic ...
Yang Liu+4 more
wiley +1 more source
Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome
Summary: The nucleosome core particle (NCP) comprises a histone octamer, wrapped around by ∼146-bp DNA, while the nucleosome additionally contains linker DNA.
Ayako Furukawa+7 more
doaj
Preferential in vitro assembly of nucleosome cores on some AT-rich regions of SV40 DNA [PDF]
Bohdan Wasylyk, P Oudet, Pierre Chambon
openalex +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Fractionation of nucleosomes by salt elution from micrococcal nuclease-digested nuclei. [PDF]
M M Sanders
openalex +1 more source
Double the Double: Revisiting BCL11B's Multimerization
ABSTRACT The transcription factor B Cell Lymphoma/Leukemia 11B (BCL11B) exerts a bi‐directional function in cancer, with its role as an emerging therapeutic target in cancer treatment being particularly intriguing. BCL11B knockouts in cultured T cells revealed the acquisition of properties characteristic of natural killer cells, hinting at its ...
Anne Susemihl+5 more
wiley +1 more source