Results 171 to 180 of about 64,059 (299)
Rapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault +5 more
wiley +1 more source
Histone packing in the nucleosome core particle of chromatin
, 1978 C. W. Carter
openalex +1 more source
The dependence of the linking number of a circular minichromosome upon the shape and the orientation of its nucleosomes [PDF]
, 1981 Sergei A. Grigoryev, L. B. Ioffe
openalex +1 more source
Glia, Volume 73, Issue 6, Page 1307-1323, June 2025.Main Points Inactivating the INO80 chromatin remodelling complex greatly extends the oligodendrocyte precursor (OP) cell cycle by prolonging G1. INO80 acts in OPs via histone H2A/H2A.Z exchange. INO80 binds the transcriptional regulator OLIG2 in OPs.
Jordan L. Wright +4 more
wiley +1 more source
Distribution of linker DNA in relation to core DNA in H1 depleted nucleosomes [PDF]
, 1981 Jean‐Jacques Lawrence +1 more
openalex +1 more source
Medicinal Research Reviews, Volume 45, Issue 3, Page 985-1015, May 2025.ABSTRACT This review provides a comprehensive overview of the role of G9a/EHMT2, focusing on its structure and exploring the impact of its pharmacological and/or gene inhibition in various neurological diseases. In addition, we delve into the advancements in the design and synthesis of G9a/EHMT2 inhibitors, which hold promise not only as a treatment ...
Aina Bellver‐Sanchis +10 more
wiley +1 more source
Escherichia coli single-strand binding protein organizes single-stranded DNA in nucleosome-like units. [PDF]
, 1982 Susan A. Chrysogelos, Jack D. Griffith
openalex +1 more source
Ethyl Pyruvate Injection Enhances the Ischaemic Zone Viability in Burn Wounds in Rats
Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.Ethyl pyruvate (EP) injection enhances burn wound healing by reducing oxidative stress, inflammation and progressive tissue necrosis. EP preserves the ischaemic stasis zone, promotes collagen synthesis and accelerates tissue regeneration, making it a promising therapeutic agent for burn treatment.
Hossein Khoori Babalhakam +4 more
wiley +1 more source
Replication-dependent histone labeling dissects the physical properties of euchromatin/heterochromatin in living human cells. [PDF]
Sci AdvMinami K +9 more
europepmc +1 more source
Cryo‐EM Structures of Native Chromatin Units From Human Cells
Genes to Cells, Volume 30, Issue 3, May 2025.We have established a method for the cryo‐EM structural analysis of native mono‐ and poly‐nucleosomes extracted from human cells. Single particle cryo‐EM and cryo‐electron tomography analyses have visualized a native nucleosome structure and secondary nucleosome arrangements in cellular chromatin.
Suguru Hatazawa +6 more
wiley +1 more source