Results 191 to 200 of about 156,001 (374)

Molecular polymorphisms that underlie trait variation in crops: Lessons learned from soybean

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Genetic variation within a germplasm is important in crop improvement, providing a foundation for breeders to develop new varieties. Traits of agronomic and economic importance are often mapped to identify the genetic basis of observed phenotypes, oftentimes using quantitative trait locus (QTL) analysis.
Mary Jane C. Espina   +2 more
wiley   +1 more source

Enhanced diagnostic accuracy of high‐grade cervical intraepithelial neoplasia in postmenopausal women through PAX1/JAM3 methylation analysis

open access: yesInternational Journal of Cancer, Volume 158, Issue 4, Page 1116-1125, 15 February 2026.
What's new? Cervical cancer screening is challenging in postmenopausal women, partly due to physiological changes that reduce the sensitivity of cytology and colposcopy. This study evaluated the diagnostic performance of combined PAX1 and JAM3 gene methylation testing in a large cohort of postmenopausal women undergoing colposcopy. Compared to cytology
Huanzi Peng   +11 more
wiley   +1 more source

Chromatin assembly extracts from Drosophila embryos. [PDF]

open access: yes, 1994
Becker, Peter B.   +2 more
core   +1 more source

Clinically Irrelevant Terminal 16q21 Deletion Detected by NIPT Is Attributable to Inherited Fragility at FRA16B

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 348-352, February 2026.
ABSTRACT Genome‐wide non‐invasive prenatal testing (NIPT) is a powerful tool for prenatal detection of the common aneuploidies causing Down‐, Edwards‐, and Patau syndrome. Its genome‐wide reach also enables the detection of unbalanced structural chromosomal abnormalities.
Servi J. C. Stevens   +9 more
wiley   +1 more source

Structural basis for nucleosome-mediated inhibition of cGAS activity

open access: yesCell Research, 2020
D. Cao   +4 more
semanticscholar   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu   +1 more
wiley   +1 more source

A genomic code for nucleosome positioning

open access: yesNature, 2006
E. Segal   +7 more
semanticscholar   +1 more source

High‐throughput single‐cell DNA methylation and chromatin accessibility co‐profiling with SpliCOOL‐seq

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen   +6 more
wiley   +1 more source

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