Results 101 to 110 of about 71,049 (222)

A study of strong nucleosomes in the human genome

iScience, 2022
Summary: Micrococcal nuclease (MNase) is widely used to map nucleosomes. However, nucleosomes are highly dynamic and susceptible to experimental conditions, resulting in extreme variability across nucleosome maps, which complicates the generation of ...
Lin Wang, Chunnan Dong, Chaolong Lu, Shujin Li, Lihong Fu, Bin Cong   +5 more
doaj  

The nature of the interaction of nucleosomes with a eukaryotic RNA polymerase II [PDF]

, 1979
David M.J. Lilley, Melanie Jacobs, Michael Houghton   +2 more
openalex   +1 more source

Fine Chromatin-Driven Mechanism of Transcription Interference by Antisense Noncoding Transcription

Cell Reports, 2020
Summary: Eukaryotic genomes are almost entirely transcribed by RNA polymerase II. Consequently, the transcription of long noncoding RNAs often overlaps with coding gene promoters, triggering potential gene repression through a poorly characterized ...
Jatinder Kaur Gill, Andrea Maffioletti, Varinia García-Molinero, Françoise Stutz, Julien Soudet   +4 more
doaj  

SF3B1 Association with Chromatin Determines Splicing Outcomes

Cell Reports, 2015
Much remains unknown concerning the mechanism by which the splicing machinery pinpoints short exons within intronic sequences and how splicing factors are directed to their pre-mRNA targets.
Nir Kfir, Galit Lev-Maor, Ohad Glaich, Adi Alajem, Arnab Datta, Siu K. Sze, Eran Meshorer, Gil Ast   +7 more
doaj   +1 more source

RSC remodeling of oligo-nucleosomes: an atomic force microscopy study [PDF]

arXiv, 2010
RSC is an essential chromatin remodeling factor that is required for the control of several processes including transcription, repair and replication. The ability of RSC to relocate centrally positioned mononucleosomes at the end of nucleosomal DNA is firmly established, but the data on RSC action on oligo-nucleosomal templates remains still scarce. By
arxiv  

Phase separation directs ubiquitination of gene-body nucleosomes

Nature, 2020
Laura D. Gallego, Maren Schneider, Chitvan Mittal, Anete Romanauska, Ricardo M. Gudino Carrillo, Tobias Schubert, B. F. Pugh, A. Köhler   +7 more
semanticscholar   +1 more source

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.

PLoS Biology, 2011
The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian cells
Barbara Celona, Assaf Weiner, Francesca Di Felice, Francesco M Mancuso, Elisa Cesarini, Riccardo L Rossi, Lorna Gregory, Dilair Baban, Grazisa Rossetti, Paolo Grianti, Massimiliano Pagani, Tiziana Bonaldi, Jiannis Ragoussis, Nir Friedman, Giorgio Camilloni, Marco E Bianchi, Alessandra Agresti   +16 more
doaj   +1 more source

Linking numbers and nucleosomes. [PDF]

, 1976
F H Crick
openalex   +1 more source

The octamer is the major form of CENP-A nucleosomes at human centromeres

Nature Structural &Molecular Biology, 2013
The centromere is the chromosomal locus that ensures fidelity in genome transmission at cell division. Centromere protein A (CENP-A) is a histone H3 variant that specifies centromere location independently of DNA sequence.
Dan Hasson, Tanya Panchenko, Kevan J. Salimian, M. U. Salman, N. Sekulić, A. Alonso, P. Warburton, B. E. Black   +7 more
semanticscholar   +1 more source

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A

Frontiers in Microbiology, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze   +12 more
doaj   +1 more source