Results 111 to 120 of about 49,625 (309)

Anticorpos anti-C1q, anticromatina/nucleossomo e anti-dsDNA em pacientes com lúpus eritematoso sistêmico juvenil Anti-C1q, anti-chromatin/nucleosome, and anti-dsDNA antibodies in juvenile systemic lupus erythematosus patients

open access: yesRevista Brasileira de Reumatologia, 2012
OBJETIVO: Avaliar a presença de anticorpos anti-C1q, anticromatina/nucleossomo e anti-DNA de duplo filamento (dsDNA) em pacientes com lúpus eritematoso sistêmico juvenil (LESJ) e controles.
Adriana Almeida de Jesus   +7 more
doaj   +1 more source

Tetrameric organization of vertebrate centromeric nucleosomes

open access: yes, 2010
Mitosis ensures equal genome segregation in the eukaryotic lineage. This process is facilitated by microtubule attachment to each chromosome via its centromere.
Emilios K. Dimitriadis   +4 more
core   +1 more source

The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes

open access: yes, 2022
CENP-A is a histone variant found in high abundance at the centromere in humans. At the centromere, this histone variant replaces the histone H3 found throughout the bulk chromatin.
Tommy Stormberg   +3 more
core   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

open access: yesJournal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Retrospective Identification and Quantitative Image Analysis of the ICAP Nuclear Pattern AC‐30 in Antinuclear Antibody Testing

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This investigation was conducted in two phases. Phase I involved the classification and clinical profiling of AC‐30. In Phase II, quantitative image analysis was performed to explore its associations with clinical parameters. ABSTRACT Background The International Consensus on ANA Patterns (ICAP) recently codified the AC‐30 nuclear pattern ...
Changmeng Wu   +5 more
wiley   +1 more source

Centromeric Nucleosomes Induce Positive DNA Supercoils

open access: yes, 2009
SummaryCentromeres of higher eukaryotes are epigenetically maintained; however, the mechanism that underlies centromere inheritance is unknown. Centromere identity and inheritance require the assembly of nucleosomes containing the CenH3 histone variant ...
Henikoff, Steven, Furuyama, Takehito
core   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Evaluation of nucleosome forming potentials (NFPs) of forensically important STRs

open access: yes, 2011
Degraded forensic samples have proved difficult to analyze and interpret. New analysis techniques are constantly being discovered and improved but researchers have overlooked the structural properties that could prevent or slow the process of degradation.
Thanakiatkrai, Phuvadol   +3 more
core   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Histone Tail Dynamics in Partially Disassembled Nucleosomes During Chromatin Remodeling

open access: yesFrontiers in Molecular Biosciences, 2019
Nucleosomes are structural units of the chromosome consisting of DNA wrapped around histone proteins, and play important roles in compaction and regulation of the chromatin structure.
Takeru Kameda   +5 more
doaj   +1 more source

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