Results 221 to 230 of about 74,179 (293)

Histone acetylation: influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression [PDF]

, 1997
Kazuhiro Ura
openalex   +1 more source

Pioneer Factor FOXA1 Boosts CHO Cell Productivity

Biotechnology Journal, Volume 21, Issue 1, January 2026.
Graphical Abstract and Lay Summary FOXA1 binds directly to the EF1α and CMV promoters that are widely used to drive transgene expression. It stimulates transcription by recruiting cofactors that manipulate the epigenetic environment, including TET1 that demethylates DNA, p300 that acetylates histones and SWI/SNF that remodels nucleosomes.
Sienna P. Butterfield, Fay L. Saunders, Robert J. White   +2 more
wiley   +1 more source

Structural basis of cyclobutane pyrimidine dimer recognition by UV-DDB in the nucleosome. [PDF]

Nat Commun
Matsumoto S, Takizawa Y, Ogasawara M, Hashimoto K, Negishi L, Xu W, Tachibana H, Yamamoto J, Iwai S, Sugasawa K, Kurumizaka H.   +10 more
europepmc   +1 more source

Customizing Native Chemical Ligation: A Case Study on Histone Variant H2A.B from Toolbox to Target

Chemistry–Methods, Volume 6, Issue 1, January 2026.
The core histone protein variant H2A.B, chosen as the target protein, is involved in many transcriptional processes regulated by its post‐translational modifications. Herein, the native chemical toolbox is harnessed to demonstrate the successful synthesis and semi‐synthesis of site‐specifically modified H2A.B variants via different strategies.
Tobias Gökler, Medine Soydan, Lydia Jane Barber, Garence Ferraton, Anne Claire Conibear   +4 more
wiley   +1 more source

Myeloperoxidase transforms chromatin into neutrophil extracellular traps. [PDF]

Nature
Burn GL, Raisch T, Tacke S, Winkler M, Prumbaum D, Thee S, Gimber N, Raunser S, Zychlinsky A.   +8 more
europepmc   +1 more source

Chromatin Profiling Reveals Distinct Male and Female Trajectories for Developmental Learning Potential

Developmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT Adult patterns of behavior can often be explained by developmental experiences. In some cases, developmental experience can have permanent influence on brain and behavior only during specific ages; these phases are called critical or sensitive periods. Epigenetic mechanisms can regulate both maturational and experiential processes in the brain
Grant W. Kunzelman, Alice Batistuzzo, Sarah E. London   +2 more
wiley   +1 more source

Structural basis of nucleosome recognition by the conserved Dsup and HMGN nucleosome-binding motif. [PDF]

Genes Dev
Alegrio-Louro J, Cruz-Becerra G, Kassavetis GA, Kadonaga JT, Leschziner AE.   +4 more
europepmc   +1 more source

Selective Anchoring of TFIID to Nucleosomes by Trimethylation of Histone H3 Lysine 4

Cell, 2007
M. Vermeulen, K. Mulder, S. Denissov, W. Pijnappel, F. V. Schaik, Radhika A. Varier, Marijke P. A. Baltissen, H. Stunnenberg, M. Mann, H. Timmers   +9 more
semanticscholar   +1 more source

DNA‐Based Liquid Biopsy for Evaluating Surgical and Postsurgical Outcomes in Gynecologic Malignancies: A Systematic Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Liquid biopsy using plasma and uterine aspirate samples provides a minimally invasive tool for detecting and monitoring gynecologic cancers. Circulating tumor DNA (ctDNA) and cell‐free DNA (cfDNA) enable prognosis, treatment response assessment, and improved diagnostic accuracy across various tumor types. ABSTRACT Introduction DNA‐based liquid biopsies,
Samaneh Yavari, Sepide Javankiani, Foroozan Yarahmadi, Rojin Sarallah, Behandokht Rezaei, Maryam Maroufi, Mona Khabbazkar Amlashi, Mahshid Imankhan, Mahnaz Marvi, Neda Aslani, Arezou Soltanattar, Zahra Mohammadi, Alireza Azani, Pegah Kavousinia   +13 more
wiley   +1 more source

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani, William Poulos, Maryam Rahimzadeh Dashtaki, Seyed Amirhossein Sadeghi, Jose B. Cibelli, Fei Fang, Liangliang Sun   +6 more
wiley   +1 more source