Results 31 to 40 of about 3,609 (205)
Prostaglandins Differentially Regulate the Constitutive and Mechanosensitive Release of Soluble Nucleotidases in the Urinary Bladder Mucosa [PDF]
International Journal of Molecular SciencesVioleta Mutafova-Yambolieva +2 more
exaly +2 more sources
Transcriptional and Metabolic Investigation in 5′-Nucleotidase Deficient Cancer Cell Lines
Cells, 2021 Enzymes of nucleoside and nucleotide metabolism regulate important cellular processes with potential impacts on nucleotide-unrelated parameters. We have used a set of CRISPR/Cas9-modified cell models expressing both, one, or none of the 5′-nucleotidases ...
Octavia Cadassou +9 more
doaj +1 more source
Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts. [PDF]
PLoS ONE, 2013 The use of topical and oral adenosine derivatives in HIV prevention that need to be maintained in tissues and cells at effective levels to prevent transmission prompted us to ask whether estradiol could influence the regulation of catabolic nucleotidase ...
Zheng Shen +7 more
doaj +1 more source
Ecto-nucleotidases as potential biomarkers for diagnosis of endometriosis [PDF]
, 2022 Introduction: Endometriosis is an inflammatory disorder characterized by the growth of endometrial tissue in extrauterine locations. Ovarian endometriomas are a common form of endometriosis.
Tresserra, Francesc +9 more
core
Neurobiology of Disease, 2021 Extracellular ATP is a danger signal to the brain and contributes to neurodegeneration in animal models of Alzheimer's disease through its extracellular catabolism by CD73 to generate adenosine, bolstering the activation of adenosine A2A receptors (A2AR).
Elisabete Augusto +11 more
doaj +1 more source
The functional logic of 5'nucleotidases [PDF]
, 2013 Adenosine- and uridine-cytidine kinases, purine-nucleoside phosphorylase, hypoxanthine-guanine phosphoribosyl transferase, and several related enzymes, are components of the salvage pathways which reduce the loss of intracellular purine and pyrimidine ...
Ipata Pl, BALESTRI, FRANCESCO
core +1 more source
Some aspects of purinergic signaling in the ventricular system of porcine brain
Acta Veterinaria Scandinavica, 2011 Background Numerous signaling pathways function in the brain ventricular system, including the most important - GABAergic, glutaminergic and dopaminergic signaling. Purinergic signalization system - comprising nucleotide receptors, nucleotidases, ATP and
Komoszyński Michał +4 more
doaj +1 more source
ISN1 Nucleotidases and HAD Superfamily Protein Fold: In silico Sequence and Structure Analysis [PDF]
, 2007 cN-II class of 5' purine nucleotidases exhibit specificity for IMP/GMP and belong to the HAD (haloacid dehalogenase) superfamily of hydrolases. The recently identified ISN1 class of IMP specific 5'-nucleotidases occurring in yeast, fungi and certain ...
Srinivasan, Bharath, Balaram, Hemalatha
core +2 more sources
Kinetic properties of the cytosolic 5′-nucleotidases IIIA, IIIB and variants of DmcN-IIIB. [PDF]
, 2014 Kinetic properties of the cytosolic 5′-nucleotidases IIIA, IIIB and variants of DmcN-IIIB.
Piotr Neumann (361820) +4 more
core +1 more source
PLoS ONE, 2019 5'-nucleotidases are widespread among all domains of life. The enzymes hydrolyze phosphate residues from nucleotides and nucleotide derivatives. In some pathobiontic bacteria, 5'-nucleotidases contribute to immune evasion by dephosphorylating adenosine ...
Marcel-Lino Dangel +6 more
doaj +1 more source