Results 11 to 20 of about 9,655 (264)

Purinergic Signaling in Pathologic Osteogenic Differentiation of Aortic Valve Interstitial Cells from Patients with Aortic Valve Calcification [PDF]

Biomedicines, 2023
Purinergic signaling is associated with a vast spectrum of physiological processes, including cardiovascular system function and, in particular, its pathological calcifications, such as aortic valve stenosis.
Polina Klauzen, Daria Semenova, Daria Kostina, Vladimir Uspenskiy, Anna Malashicheva   +4 more
doaj   +2 more sources

Mammalian 5′-Nucleotidases [PDF]

Journal of Biological Chemistry, 2003
BIANCHI, VERA, SPYCHALA J.
exaly   +4 more sources

Microbial 5′-nucleotidases: their characteristics, roles in cellular metabolism, and possible practical applications [PDF]

Applied Microbiology and Biotechnology, 2021
Natalia P Zakataeva
exaly   +2 more sources

Editorial: Adenosine metabolism in cardiovascular and smooth muscle [PDF]

Frontiers in Pharmacology
Barbara Kutryb-Zając, Barbara Kutryb-Zając, Simon C. Robson, Elisabetta Caiazzo, Elisabetta Caiazzo   +4 more
doaj   +2 more sources

Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation [PDF]

, 2013
Previous studies have shown that exogenous ATP (>1µM) prevents bone formation in vitro by blocking mineralisation of the collagenous matrix. This effect is thought to be mediated via both P2 receptor-dependent pathways and a receptor-independent ...
A Brandao-Burch, A Brandao-Burch, A Gartland, A Hoebertz, BA Evans, CG Bellows, DC Genetos, DC Genetos, E Nakamura, G Burnstock, G Burnstock, G Burnstock, G Burnstock, H Fleisch, H Fleisch, H Zimmermann, IR Orriss, IR Orriss, IR Orriss, IR Orriss, IR Orriss, IR Orriss, IR Orriss, Isabel R. Orriss, J Ham, JL Ramírez-Zacarías, JP Reyes, KA Buckley, KA Buckley, KA Johnson, L Hessle, Luc Malaval, M Ciciarello, M Romanello, Mark O. R. Hajjawi, Michelle L. Key, MP Abbracchio, MW Pfaffl, N Panupinthu, N Panupinthu, N Wang, N Zippel, RM Rumney, S Shimegi, S Syberg, Timothy R. Arnett, V Ralevic, WB Bowler, WE Razzell, WN Addison   +49 more
core   +12 more sources

Mechanosensitive TRPV4 Channel-Induced Extracellular ATP Accumulation at the Acupoint Mediates Acupuncture Analgesia of Ankle Arthritis in Rats

Life, 2021
(1) Background: Acupuncture (AP) is a safe and effective analgesic therapy. Understanding how fine needles trigger biological signals can help us optimize needling manipulation to improve its efficiency.
Yawen Zheng, Weimin Zuo, Dan Shen, Kaiyu Cui, Meng Huang, Di Zhang, Xueyong Shen, Lina Wang   +7 more
doaj   +1 more source

Spatial mapping of ectonucleotidase gene expression in the murine urinary bladder

Frontiers in Physiology, 2023
Purinergic signaling is important for normal bladder function, as it is thought to initiate the voiding reflex and modulate smooth muscle tone. The availability of adenine nucleotides and nucleosides (aka purines) at receptor sites of various cell types ...
Mafalda S. L. Aresta Branco, Brian A. Perrino, Violeta N. Mutafova-Yambolieva   +2 more
doaj   +1 more source

Evidence for a Cross-Talk Between Cytosolic 5′-Nucleotidases and AMP-Activated Protein Kinase

Frontiers in Pharmacology, 2020
Marcella Camici, Mercedes García-Gil, Simone Allegrini   +2 more
exaly   +3 more sources

The combined effect of environmental and host factors on the emergence of viral RNA recombinants. [PDF]

PLoS Pathogens, 2010
Viruses are masters of evolution due to high frequency mutations and genetic recombination. In spite of the significance of viral RNA recombination that promotes the emergence of drug-resistant virus strains, the role of host and environmental factors in
Hannah M Jaag, Peter D Nagy
doaj   +1 more source

Methyl jasmonate elicitation of common bean seedlings induces nucleotidase activity and the expression of several nucleotidase genes in radicles

Biologia Plantarum, 2021
Nucleotides are the basic elements of the genetic material, participate in bio-energetic processes, are cofactors and components of secondary metabolites, etc. Nucleotide hydrolases (nucleotidases) are phosphatases that remove the 5'-phosphate group from
G. GALVEZ-VALDIVIESO, M. GARMENDIA-CALVO, M. PINEDA, P. PIEDRAS   +3 more
doaj   +1 more source