Results 21 to 30 of about 3,609 (205)
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
The combined effect of environmental and host factors on the emergence of viral RNA recombinants. [PDF]
Viruses are masters of evolution due to high frequency mutations and genetic recombination. In spite of the significance of viral RNA recombination that promotes the emergence of drug-resistant virus strains, the role of host and environmental factors in
Hannah M Jaag, Peter D Nagy
doaj +1 more source
Nucleotides are the basic elements of the genetic material, participate in bio-energetic processes, are cofactors and components of secondary metabolites, etc. Nucleotide hydrolases (nucleotidases) are phosphatases that remove the 5'-phosphate group from
G. GALVEZ-VALDIVIESO +3 more
doaj +1 more source
E-NTPDases: Possible Roles on Host-Parasite Interactions and Therapeutic Opportunities
Belonging to the GDA1/CD39 protein superfamily, nucleoside triphosphate diphosphohydrolases (NTPDases) catalyze the hydrolysis of ATP and ADP to the monophosphate form (AMP) and inorganic phosphate (Pi).
Lisvane Paes-Vieira +3 more
doaj +1 more source
REIS1–4 has demonstrated the presence of a phosphatase in various tissues specifically hydrolysing 5-nucleotides, for example, adenosine-5-phosphate. One of us has previously reported5 that normal blood serum has a low 5-nucleotidase activity corresponding to about 1/10 of its non-specific alkaline phosphatase activity towards glycerophosphate. In bone
T F, DIXON, M, PURDON
openaire +3 more sources
Identification, Heterologous Expression, and Functional Characterization of Bacillus subtilis YutF, a HAD Superfamily 5'-Nucleotidase with Broad Substrate Specificity. [PDF]
5'-nucleotidases (EC 3.1.3.5) catalyze the hydrolytic dephosphorylation of 5'-ribonucleotides and 5'-deoxyribonucleotides as well as complex nucleotides, such as uridine 5'-diphosphoglucose (UDP-glucose), nicotinamide adenine dinucleotide and flavin ...
Natalia P Zakataeva +5 more
doaj +1 more source
Cytosolic 5′-nucleotidases II (cNT5-II) are an evolutionary conserved family of 5′-nucleotidases that catalyze the intracellular hydrolysis of nucleotides.
Euginia L. Singgih +5 more
doaj +1 more source
Kinetic properties of the cytosolic 5′-nucleotidases IIIA and IIIB. [PDF]
Kinetic properties of the cytosolic 5′-nucleotidases IIIA and IIIB.
Piotr Neumann (361820) +4 more
core +1 more source
Ecto-nucleotidase activities of promastigotes from Leishmania (Viannia) braziliensis relates to parasite infectivity and disease clinical outcome. [PDF]
BACKGROUND: Leishmania (Viannia) braziliensis has been associated with a broad range of clinical manifestations ranging from a simple cutaneous ulcer to destructive mucosal lesions.
Pauline M Leite +12 more
doaj +1 more source
Model of urinary bladder showing differential distribution of nucleotidases. [PDF]
Three tissue layers of the bladder are shown with the cells we have identified as expressing nucleotidases. For the sake of clarity, afferent and efferent neurons have not been included. Different cell types are color coded with the banner arrows at left
Weiqun Yu (299931) +2 more
core +1 more source

