Results 21 to 30 of about 3,609 (205)

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

The combined effect of environmental and host factors on the emergence of viral RNA recombinants. [PDF]

open access: yesPLoS Pathogens, 2010
Viruses are masters of evolution due to high frequency mutations and genetic recombination. In spite of the significance of viral RNA recombination that promotes the emergence of drug-resistant virus strains, the role of host and environmental factors in
Hannah M Jaag, Peter D Nagy
doaj   +1 more source

Methyl jasmonate elicitation of common bean seedlings induces nucleotidase activity and the expression of several nucleotidase genes in radicles

open access: yesBiologia Plantarum, 2021
Nucleotides are the basic elements of the genetic material, participate in bio-energetic processes, are cofactors and components of secondary metabolites, etc. Nucleotide hydrolases (nucleotidases) are phosphatases that remove the 5'-phosphate group from
G. GALVEZ-VALDIVIESO   +3 more
doaj   +1 more source

E-NTPDases: Possible Roles on Host-Parasite Interactions and Therapeutic Opportunities

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Belonging to the GDA1/CD39 protein superfamily, nucleoside triphosphate diphosphohydrolases (NTPDases) catalyze the hydrolysis of ATP and ADP to the monophosphate form (AMP) and inorganic phosphate (Pi).
Lisvane Paes-Vieira   +3 more
doaj   +1 more source

Serum 5-Nucleotidase [PDF]

open access: yesNature, 1952
REIS1–4 has demonstrated the presence of a phosphatase in various tissues specifically hydrolysing 5-nucleotides, for example, adenosine-5-phosphate. One of us has previously reported5 that normal blood serum has a low 5-nucleotidase activity corresponding to about 1/10 of its non-specific alkaline phosphatase activity towards glycerophosphate. In bone
T F, DIXON, M, PURDON
openaire   +3 more sources

Identification, Heterologous Expression, and Functional Characterization of Bacillus subtilis YutF, a HAD Superfamily 5'-Nucleotidase with Broad Substrate Specificity. [PDF]

open access: yesPLoS ONE, 2016
5'-nucleotidases (EC 3.1.3.5) catalyze the hydrolytic dephosphorylation of 5'-ribonucleotides and 5'-deoxyribonucleotides as well as complex nucleotides, such as uridine 5'-diphosphoglucose (UDP-glucose), nicotinamide adenine dinucleotide and flavin ...
Natalia P Zakataeva   +5 more
doaj   +1 more source

Investigating cytosolic 5′-nucleotidase II family genes as candidates for neuropsychiatric disorders in Drosophila (114/150 chr)

open access: yesTranslational Psychiatry, 2021
Cytosolic 5′-nucleotidases II (cNT5-II) are an evolutionary conserved family of 5′-nucleotidases that catalyze the intracellular hydrolysis of nucleotides.
Euginia L. Singgih   +5 more
doaj   +1 more source

Kinetic properties of the cytosolic 5′-nucleotidases IIIA and IIIB. [PDF]

open access: yes, 2014
Kinetic properties of the cytosolic 5′-nucleotidases IIIA and IIIB.
Piotr Neumann (361820)   +4 more
core   +1 more source

Ecto-nucleotidase activities of promastigotes from Leishmania (Viannia) braziliensis relates to parasite infectivity and disease clinical outcome. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
BACKGROUND: Leishmania (Viannia) braziliensis has been associated with a broad range of clinical manifestations ranging from a simple cutaneous ulcer to destructive mucosal lesions.
Pauline M Leite   +12 more
doaj   +1 more source

Model of urinary bladder showing differential distribution of nucleotidases. [PDF]

open access: yes, 2013
Three tissue layers of the bladder are shown with the cells we have identified as expressing nucleotidases. For the sake of clarity, afferent and efferent neurons have not been included. Different cell types are color coded with the banner arrows at left
Weiqun Yu (299931)   +2 more
core   +1 more source

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