Results 101 to 110 of about 525,575 (332)

Nucleus accumbens response to gains in reputation for the self relative to gains for others predicts social media use

Frontiers in Human Neuroscience, 2013
Our reputation is important to us; we’ve experienced natural selection to care about our reputation. Recently, the neural processing of gains in reputation (positive social feedback concerning one’s character) has been shown to occur in the human ventral
Dar eMeshi, Dar eMeshi, Dar eMeshi, Dar eMeshi, Carmen eMorawetz, Carmen eMorawetz, Carmen eMorawetz, Hauke R Heekeren, Hauke R Heekeren, Hauke R Heekeren, Hauke R Heekeren   +10 more
doaj   +1 more source

The Selective Bromodomain and Extra-Terminal Domain (BET) Inhibitor RVX-208 Reduces Cocaine-Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens. [PDF]

Addict Biol
Rats treated with the domain‐selective BET inhibitor RVX‐208 during a 2‐week forced abstinence period exhibited a reduction in cocaine‐seeking behaviour but not sucrose seeking or open field behaviour. This treatment effect was associated with proteomic changes in pathways relevant to dopaminergic and glutamatergic signalling in the nucleus accumbens ...
Sacko TJ, Seyednejad A, Engelhardt J, Sartor GC.   +3 more
europepmc   +2 more sources

Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens

International Journal of Neuropsychopharmacology, 2015
Background: Chronic ethanol exposure reduces dopamine transmission in the nucleus accumbens, which may contribute to the negative affective symptoms associated with ethanol withdrawal.
J. Rose, Anushree N. Karkhanis, Rong Chen, D. Gioia, Marcelo F. Lopez, H. Becker, B. McCool, S. Jones   +7 more
semanticscholar   +1 more source

Transcriptome profiles associated with resilience and susceptibility to single prolonged stress in the locus coeruleus and nucleus accumbens in male sprague-dawley rats

, 2022
Roxanna J. Nahvi, Arax Tanelian, Chiso Nwokafor, Arthur Godino, Eric M. Parise, Molly Estill, Li Shen, Eric J. Nestler, Esther L. Sabban   +8 more
openalex   +2 more sources

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Alterations in subcortical magnetic susceptibility and disease-specific relationship with brain volume in major depressive disorder and schizophrenia

Translational Psychiatry
Quantitative susceptibility mapping is a magnetic resonance imaging technique that measures brain tissues’ magnetic susceptibility, including iron deposition and myelination.
Shuhei Shibukawa, Hirohito Kan, Shiori Honda, Masataka Wada, Ryosuke Tarumi, Sakiko Tsugawa, Yui Tobari, Norihide Maikusa, Masaru Mimura, Hiroyuki Uchida, Yuko Nakamura, Shinichiro Nakajima, Yoshihiro Noda, Shinsuke Koike   +13 more
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

Journal of Neuroscience, 2015
Previous studies have shown that chronic cocaine administration induces SIRT1, a Class III histone deacetylase, in the nucleus accumbens (NAc), a key brain reward region, and that such induction influences the gene regulation and place conditioning ...
D. Ferguson, Ning-Yi Shao, E. Heller, Jian Feng, R. Neve, Hee-Dae Kim, Tanessa Call, S. Magazu, Li Shen, E. Nestler   +9 more
semanticscholar   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Reliability of Glutamate Quantification in Human Nucleus Accumbens Using Proton Magnetic Resonance Spectroscopy at a 70-cm Wide-Bore Clinical 3T MRI System

Frontiers in Neuroscience, 2017
The human nucleus accumbens is a challenging region to study using proton magnetic resonance spectroscopy (1H-MRS) on a 70-cm wide-bore clinical 3T MRI system.
Xi-Long Liu, Long Li, Jian-Neng Li, Jia-Hui Rong, Bo Liu, Ze-Xuan Hu   +5 more
doaj   +1 more source