Results 111 to 120 of about 525,575 (332)
Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner [PDF]
, 2021 Javier Orihuel +5 more
openalex +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori +7 more
wiley +1 more source
¿Cómo funciona el nucleus accumbens? [PDF]
Revista de Neurología, 2000 O nucleus accumbens é considerado uma interfase neural entre a motivaçao, conduta sexual, resposta ao stress, autoadministraçao de drogas, etc. Desenvolvimento. O nucleus accumbens apresenta dois territórios, o núcleus e a cobertura, cujas conexoes desenham nitidamente as suas vertentes motora e límbica.
openaire +3 more sources
British Journal of Pharmacology, EarlyView.Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang +2 more
wiley +1 more source
Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice
Basic and Clinical Neuroscience, 2015 Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate
Naser Osanloo +5 more
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Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, EarlyView.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata +13 more
wiley +1 more source
Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity
Neuron, 2020 Michelle Corkrum +13 more
semanticscholar +1 more source
Rewarding Effects of Operant Dry-Licking Behavior on Neuronal Firing in the Nucleus Accumbens Core [PDF]
, 2017 Enrico Patrono +6 more
openalex +1 more source