Results 161 to 170 of about 525,575 (332)

Subcortical Brain‐Age Gaps Reveal Asymmetric Aging Patterns in Parkinson's Disease With Cognitive Impairment

Brain and Behavior, Volume 16, Issue 1, January 2026.
Accelerated brain aging in Parkinson's disease is not global but a localized, asymmetric process in the left limbic‐cholinergic network. Regional brain‐age metrics offer a sensitive biomarker for detecting the specific neurodegeneration linked to cognitive decline.
Sadegh Ghaderi, Ali Fathi Jouzdani, Ali Mohammad Pourbagher‐Shahri, Sana Mohammadi   +3 more
wiley   +1 more source

Differences in the Efficacy of Cognitive Function Treatment Related to Functional Patterns in the Frontal‐Limbic Network in Patients With Bipolar Disorder

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Graphical Abstract of Differences in the Efficacy of Cognitive Function Treatment Related to Functional Patterns in the Frontal‐Limbic Network in Patients with Bipolar Disorder. ABSTRACT Background This study aimed to identify neurobiomarkers that predict the efficacy of treatment of cognition in patients with bipolar disorder (BD).
Sujuan Li, Yangpan Ou, Haiping Liu, Qianyu Dong, Yan Qiu, Ziwei Teng, Hui Tang, Hui Xiang, Guowei Wu, Jindong Chen, Bolun Wang, Lutao Jiang, Haishan Wu   +12 more
wiley   +1 more source

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao, Yixin Fu, Tianhao Liu, Zanhao Yang, Zhengzhong Yang, Bingqing Chen, Lipeng Zhou, Juntao Yang, Duo Chen, Xiaojiao Han, Ying Tang, Jiang‐Hong Ye, Chao‐Yu Miao, Rao Fu   +13 more
wiley   +1 more source

Nucleus accumbens changes in amyotrophic lateral sclerosis. [PDF]

, 2023
Ioannis N. Mavridis, George Konstantakopoulos   +1 more
openalex  

A Novel NLRP3 Inhibitor AMS‐17 Rescues Deficits in Long‐Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

Hippocampus, Volume 36, Issue 1, January 2026.
ABSTRACT Traumatic brain injury (TBI) is a leading cause of long‐term disability, with limited effective treatment options. A key factor of TBI pathophysiology is neuroinflammation, which can involve the activation of the nucleotide‐binding domain leucine‐rich repeat protein 3 (NLRP3) inflammasome. Aberrant inflammation following injury has the ability
Eric Eyolfson, Luis Bettio, Justin Brand, Naveen Kumar Gupta, Emily Hamer, Ryan Salas, Amol Kulkarni, Brian R. Christie   +7 more
wiley   +1 more source

D1 and D2 neurons in medial nucleus accumbens participate in chronic orofacial pain phenotypes. [PDF]

Pain Rep
Montes-Ángeles CD, Andrade-González RD, Perrusquia-Hernández E, González-Alva P, García-Hernández AL, Pérez-Martínez IO.   +5 more
europepmc   +1 more source

The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder

Neuropsychopharmacology, 2017
C. Abdallah, A. Jackowski, R. Salas, Swapnil Gupta, J. Sato, X. Mao, J. Coplan, D. Shungu, S. Mathew   +8 more
semanticscholar   +1 more source

Choline transporter hemizygosity results in diminished basal extracellular dopamine levels in nucleus accumbens and blunts dopamine elevations following cocaine or nicotine

, 2013
Yu Dong, John A. Dani, Randy Blakely
openalex   +2 more sources

Cocaine Self-administration and Extinction Inversely Alter Neuron to Glia Exosomal Dynamics in the Nucleus Accumbens [PDF]

, 2020
Rachel Jarvis, Alessandra Tamashiro Orrego, Vanessa Promes, Leona Tu, Jinyuan Shi, Yongjie Yang   +5 more
openalex   +1 more source

MR‐ARFI to evaluate intensity variability and enhance targeting of FUS: A brain study in rats

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 474-484, January 2026.
Abstract Purpose Inconsistencies in focused ultrasound (FUS) transducer positioning and skull‐induced aberrations can reduce the targeting accuracy and cause inconsistencies in the intensity delivered during FUS neuromodulation procedures. This study aimed to evaluate the use of MR‐acoustic radiation force imaging (MR‐ARFI) in improving the targeting ...
Abubakr Eldirdiri, Linda Chang, David A. Martin, Eric Cunningham, Segun Bernard, Donna J. Calu, Kim Butts Pauly, Thomas Ernst   +7 more
wiley   +1 more source