Results 21 to 30 of about 525,575 (332)

Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accumbens

Molecular Brain, 2022
Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system.
Daisuke Sato, Yusuke Hamada, Michiko Narita, Tomohisa Mori, Hiroyuki Tezuka, Yukari Suda, Kenichi Tanaka, Sara Yoshida, Hideki Tamura, Akihiro Yamanaka, Emiko Senba, Naoko Kuzumaki, Minoru Narita   +12 more
doaj   +1 more source

Low frequency deep brain stimulation of nucleus accumbens shell neuronal subpopulations attenuates cocaine seeking selectively in male rats

Addiction Neuroscience, 2023
The present study examined the effect of deep brain stimulation (DBS) in the nucleus accumbens shell on cocaine seeking and neuronal plasticity in rats.
Sarah E. Swinford-Jackson, Matthew T. Rich, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce   +7 more
doaj   +1 more source

Nucleus accumbens facilitates nociception [PDF]

Experimental Neurology, 2011
We have previously demonstrated an opioid link in nucleus accumbens (NAc) that mediates antinociception produced by a novel ascending pain modulation pathway. For example, noxious stimulation induces heterosegmental antinociception that is mediated by both mu- and delta-opioid receptors in NAc.
Robert W, Gear, Jon D, Levine
openaire   +2 more sources

Glutamate Afferents From the Medial Prefrontal Cortex Mediate Nucleus Accumbens Activation by Female Sexual Behavior

Frontiers in Behavioral Neuroscience, 2019
Low levels of desire and arousal are the primary sexual dysfunctions in women, necessitating neurobiological studies of sexual motivation in female animal models.
Kelsey M. Moore, Wyatt L. Oelberg, M. Rose Glass, Matthew D. Johnson, Laura E. Been, Robert L. Meisel   +5 more
doaj   +1 more source

Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion

Molecular Psychiatry, 2019
Deficits in decoding rewarding (and aversive) signals are present in several neuropsychiatric conditions such as depression and addiction, emphasising the importance of studying the underlying neural circuits in detail.
C. Soares-Cunha, Nivaldo A. P. de Vasconcelos, B. Coimbra, A. V. Domingues, J. Silva, E. Loureiro-Campos, Rita Gaspar, I. Sotiropoulos, N. Sousa, A. Rodrigues   +9 more
semanticscholar   +1 more source

463 Childhood Emotional Neglect on Nucleus Accumbens Connectivity in Adult Survivors of Trauma

Journal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Neuroimaging research has found that childhood maltreatment is related to reduced activation of the nucleus accumbens. The long-lasting impact of this relationship is not as well understood.
Michael T. Liuzzi, Farah Harb, Kevin Petranu, Christine L. Larson   +3 more
doaj   +1 more source

Dysconnectivity of the parafascicular nucleus in Parkinson's disease: A dynamic causal modeling analysis

Neurobiology of Disease, 2023
Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen, Junyan Sun, Linlin Gao, Junling Wang, Jinghong Ma, Erhe Xu, Dongling Zhang, Liang Li, Tao Wu   +8 more
doaj   +1 more source

A case of musical preference for Johnny Cash following deep brain stimulation of the nucleus accumbens

Frontiers in Behavioral Neuroscience, 2014
Music is among all cultures an important part of the live of most people. Music has psychological benefits and may generate strong emotional and physiological responses.
Mariska eMantione, Martijn eFigee, Damiaan eDenys   +2 more
doaj   +1 more source

Nucleus Accumbens Modulation in Reward and Aversion

Cold Spring Harbor Symposia on Quantitative Biology, 2019
The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is
A. Klawonn, R. Malenka
semanticscholar   +1 more source

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

PLoS ONE, 2016
The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticity ...
Kellie S. Gross, Dieter D. Brandner, Luis A Martinez, M. Olive, R. Meisel, P. Mermelstein   +5 more
semanticscholar   +1 more source