Results 81 to 90 of about 566,734 (334)
Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man
Significance We reveal prominent delta oscillations in the nucleus accumbens preceding food reward in mice and use them to guide responsive neurostimulation to suppress binge-like behavior.
Hemmings C. H. Wu+14 more
semanticscholar +1 more source
Effort discounting in human nucleus accumbens [PDF]
A great deal of behavioral and economic research suggests that the value attached to a reward stands in inverse relation to the amount of effort required to obtain it, a principle known as effort discounting. In the present article, we present the first direct evidence for a neural analogue of effort discounting.
Stacy Huffstetler+2 more
openaire +3 more sources
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Background: Cost-benefit decision-making is a one of the decision-making models in which the animal achieves a final benefit (reward) by evaluating the cost (effort or delay).
Saeedeh Nasrollahi+3 more
doaj
Background Calcium/calmodulin-dependent protein kinase IV (CaMKIV) controls activity-dependent gene transcription by regulating the activity of the cyclic AMP response element binding protein (CREB). This signaling pathway is involved in gating emotional
Bading Hilmar+4 more
doaj +1 more source
Is Deep Brain Stimulation a viable treatment for substance-related addiction? [PDF]
For the ability to modulate the activity of dysregulated networks Deep Brain Stimulation (DBS) of areas involved in reward system and motivational states may have a potential application in addiction despite risks associated with its invasiveness.
Giusy Guzzi+3 more
doaj +1 more source
Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]
Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb+14 more
core +1 more source
Infant Death due to Cannabis Ingestion
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto+9 more
wiley +1 more source
Ensemble coding in the nucleus accumbens [PDF]
The nucleus accumbens may be involved in cognitive functions via its control of thalamocortical activity feeding back to the prefrontal cortex. Functional neuronal ensembles, or changes in the spatial and temporal distribution of active and inactive neurons, may mediate information processing in the accumbens.
openaire +2 more sources
ABSTRACT Background Eating disorders (EDs) are serious psychiatric disorders characterized by impairments in neurocognition and altered brain structure. To date the majority of studies have investigated these in acutely ill or recovered individuals.
E. Pappaianni+6 more
wiley +1 more source