Results 31 to 40 of about 378 (120)

Prefrontal and hippocampal theta rhythm show anxiolytic‐like changes during periaqueductal‐elicited “panic” in rats

Hippocampus, Volume 32, Issue 9, Page 679-694, September 2022., 2022
Abstract Anxiety and panic are both elicited by threat and co‐occur clinically. But, at the neural level, anxiety appears to inhibit the generation of panic; and vice versa. Anxiety and panic are thought to engage more anterior (a) and mid‐posterior (m) parts of the periaqueductal gray (PAG), respectively.
Carlos Silva, Calvin K. Young, Neil McNaughton   +2 more
wiley   +1 more source

Cellular resolution anatomical and molecular atlases for prenatal human brains

Journal of Comparative Neurology, Volume 530, Issue 1, Page 6-503, January 2022., 2022
Detailed cellular resolution anatomical atlases are generated for prenatal human brains at postconceptional weeks (PCW) 15 and 21 based on combined analysis of Nissl preparation, acetylcholinesterase staining, and a lot of gene markers. Using the anatomical atlases as a guide, spatial expression of 37 and 5 genes (out of 43 genes) from the brains ...
Song‐Lin Ding, Joshua J. Royall, Phil Lesnar, Benjamin A.C. Facer, Kimberly A. Smith, Yina Wei, Kristina Brouner, Rachel A. Dalley, Nick Dee, Tim A. Dolbeare, Amanda Ebbert, Ian A. Glass, Nika H. Keller, Felix Lee, Tracy A. Lemon, Julie Nyhus, Julie Pendergraft, Robert Reid, Melaine Sarreal, Nadiya V. Shapovalova, Aaron Szafer, John W. Phillips, Susan M. Sunkin, John G. Hohmann, Allan R. Jones, Michael J. Hawrylycz, Patrick R. Hof, Lydia Ng, Amy Bernard, Ed S. Lein   +29 more
wiley   +1 more source

Regular theta‐firing neurons in the nucleus incertus during sustained hippocampal activation [PDF]

European Journal of Neuroscience, 2015
Abstract This paper describes the existence of theta‐coupled neuronal activity in the nucleus incertus ( NI ). Theta rhythm is relevant for cognitive processes such as spatial navigation and memory processing, and can be recorded in a number of structures related to the ...
Sergio, Martínez-Bellver, Ana, Cervera-Ferri, Joana, Martínez-Ricós, Amparo, Ruiz-Torner, Aina, Luque-Garcia, Aina, Luque-Martinez, Arantxa, Blasco-Serra, Juan, Guerrero-Martínez, Manuel, Bataller-Mompeán, Vicent, Teruel-Martí   +9 more
openaire   +5 more sources

Sex differences in amygdalohippocampal oscillations and neuronal activation in a rodent anxiety model and in response to infralimbic deep brain stimulation

Frontiers in Behavioral Neuroscience, 2023
IntroductionDepression and anxiety are highly comorbid mental disorders with marked sex differences. Both disorders show altered activity in the amygdala, hippocampus, and prefrontal cortex.
Hanna Vila-Merkle, Alicia González-Martínez, Rut Campos-Jiménez, Joana Martínez-Ricós, Vicent Teruel-Martí, Ana Lloret, Arantxa Blasco-Serra, Ana Cervera-Ferri   +7 more
doaj   +1 more source

GABAergic Neurons in the Rat Medial Septal Complex Express Relaxin-3 Receptor (RXFP3) mRNA

Frontiers in Neuroanatomy, 2018
The medial septum (MS) complex modulates hippocampal function and related behaviors. Septohippocampal projections promote and control different forms of hippocampal synchronization.
Hector Albert-Gascó, Hector Albert-Gascó, Sherie Ma, Sherie Ma, Francisco Ros-Bernal, Ana M. Sánchez-Pérez, Andrew L. Gundlach, Andrew L. Gundlach, Francisco E. Olucha-Bordonau   +8 more
doaj   +1 more source

Evidence of D2 receptor expression in the nucleus incertus of the rat

Physiology & Behavior, 2015
The nucleus incertus (NI), located in the caudal brainstem, mainly consists of GABAergic neurons with widespread projections across the brain. It is the chief source of relaxin-3 in the mammalian brain and densely expresses corticotropin-releasing factor type 1 (CRF1) receptors.
Kumar, Jigna Rajesh, Rajkumar, Ramamoorthy, Farooq, Usman, Lee, Liying Corinne, Tan, Francis Chee Kuan, Dawe, Gavin S.   +5 more
openaire   +2 more sources

Transcriptional characterization of relaxin‐3‐positive neurons in aging and Alzheimer’s disease [PDF]

Alzheimers Dement
Abstract Background Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder worldwide and is characterized by clinical symptoms that include deficits in memory and cognition. There is an urgent need to better identify the neural networks that govern cognitive processes in humans and how they are impacted by AD pathology. The brainstem
de Avila C, Nolz J, Khatri D, Uzum Z, Intorcia A, Serrano G, Beach T, Gundlach A, Mastroeni D.   +8 more
europepmc   +2 more sources

Nucleus incertus contribution to hippocampal theta rhythm generation

European Journal of Neuroscience, 2006
AbstractThe hippocampal theta rhythm is generated by the pacemaker activity of the medial septum‐diagonal band of Broca (MS/DBB) neurons. These nuclei are influenced by brainstem structures that modulate the theta rhythm. The aim of the present work is to determine whether the nucleus incertus (NI), which has important anatomical connections with the ...
A, Nuñez, A, Cervera-Ferri, F, Olucha-Bordonau, A, Ruiz-Torner, V, Teruel   +4 more
openaire   +3 more sources

Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats

Neuropharmacology, 2016
Alcoholism is a chronic relapsing disorder and a major global health problem. Stress is a key precipitant of relapse in human alcoholics and in animal models of alcohol seeking. The brainstem nucleus incertus (NI) contains a population of relaxin-3 neurons that are highly responsive to psychological stressors; and the ascending NI relaxin-3/RXFP3 ...
Kastman, Hanna E., Błasiak, Anna, Walker, Leigh, Siwiec, Marcin, Krstew, Elena V., Gundlach, Andrew L., Lawrence, Andrew J.   +6 more
openaire   +3 more sources

Septal projections to nucleus incertus in the rat: Bidirectional pathways for modulation of hippocampal function [PDF]

Journal of Comparative Neurology, 2014
ABSTRACTProjections from the nucleus incertus (NI) to the septum have been implicated in the modulation of hippocampal theta rhythm. In this study we describe a previously uncharacterized projection from the septum to the NI, which may provide feedback modulation of the ascending circuitry.
Sánchez-Pérez, Ana María, Arnal Vicente, Isabel, Santos, F. N., Pereira, C. W., El Mlili, Nisrin, Sanjuán, Julio, Ma, Sherie, Gundlach, Andrew Lawrence, Olucha-Bordonau, Francisco E   +8 more
openaire   +2 more sources