Results 91 to 100 of about 18,919 (201)

MRI Signal Void in Degenerated Canine Intervertebral Disks May Represent Mineralization or Gas

Veterinary Radiology &Ultrasound, Volume 67, Issue 1, January 2026.
ABSTRACT Accurate interpretation of intradiskal signal voids on magnetic resonance imaging (MRI) is essential to avoid misdiagnosis and improve diagnostic decision‐making in canine spinal imaging. Gas accumulation within the degenerated canine intervertebral disk (IVD), known as vacuum phenomenon (VP), and IVD mineralization are common findings in ...
Yasamin Vali, Carola Daniel, Eberhard Ludewig, Tobias Schwarz   +3 more
wiley   +1 more source

Sulforaphane Delays Intervertebral Disc Degeneration by Alleviating Endoplasmic Reticulum Stress in Nucleus Pulposus Cells via Activating Nrf-2/HO-1 [PDF]

, 2023
Xiao Lu, Guangyu Xu, Zhidi Lin, Jian Song, Yuxuan Zhang, Hongli Wang, Feizhou Lu, Xinlei Xia, Xiaosheng Ma, Fei Zou, Jianyuan Jiang   +10 more
openalex   +1 more source

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Biomimetic Hydrogels for In Vitro Modelling of Nucleus Pulposus Degeneration: Effects of Extracellular Matrix Compositional Change on Physicochemical Properties and Cell Phenotype

Journal of Functional Biomaterials
The intervertebral disc, an anatomical compartment interposed between vertebral bodies, plays a key role in spine flexibility and compression loading.
Narjes Rashidi, Nicholas Dowell, Derek Covill, John Shepperd, Matteo Santin   +4 more
doaj   +1 more source

MRI Predictors for Improvement Without Any Intervention of Clinical Symptoms in Patients With Lumbar Disc Herniation, Questioning the True Need for Surgery

Radiology Research and Practice, Volume 2026, Issue 1, 2026.
Introduction Spontaneous resorption of a herniated lumbar disc and disappearance of clinical symptoms without repair is a well‐known but not well‐studied phenomenon. This prospective study uses magnetic resonance images to search for predictors as to the possibility of spontaneous herniation resorption without any intervention and patients ...
Andrea Šprláková-Puková, Matej Straka, Tereza Habas, Adam Čellár, Marek Dostál, Tamara Barusová, Marek Sova, Soňa Kryštofová, Martin Smrčka, Kuo Feng Hung   +9 more
wiley   +1 more source

BIOCHEMICAL AND BIOMECHANICAL SUBSTANTIATION OF REPARATIVE REGENERATION OF INTERVERTEBRAL DISCS IN PATIENTS WITH DEGENERATIVE DISC DISEASES

Східноукраїнський медичний журнал, 2020
Degenerative disc diseases occupy the second place in the overall structure of morbidity with temporary disability. In 40% of patients with spinal osteochondrosis, diseases of the locomotor apparatus and connective tissue cause primary disability.
J. A. Bodnarchuk, M. V. Khyzhnjak, О. О. Potapov, N. G. Chopik   +3 more
doaj  

Decellularized nucleus pulposus matrix/chitosan hybrid hydrogel combined with nucleus pulposus stem cells and GDF5-loaded microspheres for intervertebral disc degeneration prevention

Molecular Medicine
Background Intervertebral disc degeneration (IDD) is considered an important pathological basis for spinal degenerative diseases. Tissue engineering is a powerful therapeutic strategy that can effectively restore the normal biological properties of disc ...
Tao Ma, Chen Liu, Quanlai Zhao, Yu Zhang, Liang Xiao   +4 more
doaj   +1 more source

Neferine alleviates intervertebral disc degeneration through KEAP1/NRF2/GPX4 and NF-κB signaling pathways

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To investigate the therapeutic effects of neferine (Nef) on intervertebral disc degeneration (IDD) and the underlying regulatory pathways.Methods·The effects of Nef on the viability and proliferation of nucleus pulposus cells were assessed ...
WAN Hongjin, HU Yibin, WANG Xin, ZHANG Kai, QIN An, MA Peixiang, MA Hui, ZHAO Jie   +7 more
doaj   +1 more source

Biphasic Behavior of Nucleus Pulposus of the Lumbar Intervertebral Disc

, 2002
Madoka Otake, Shigeru TADANO
openalex   +2 more sources

Mechanical characterization and design of biomaterials for nucleus pulposus replacement and regeneration [PDF]

, 2023
Z. Li, Qiuji Lu, John Robert Honiball, Sandra Hiu‐Tung Wan, Kwk Yeung, Kmc Cheung   +5 more
openalex   +1 more source