Results 101 to 110 of about 494,442 (303)

Intelligent peptide‐based nanomaterials for targeted antibacterial therapy: Design, properties and applications

open access: yesResponsive Materials, EarlyView.
This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou   +8 more
wiley   +1 more source

The study of quark-gluon matter in high-energy nucleus-nucleus collisions [PDF]

open access: yes, 2012
A short overview is given on the study of hot matter produced in relativistic nucleus-nucleus collisions, with emphasis on recent measurements at the LHC.
arxiv   +1 more source

A novel magnetic resonance imaging postprocessing technique for the assessment of intervertebral disc degeneration-Correlation with histological grading in a rabbit disc degeneration model. [PDF]

open access: yes, 2019
Introduction:Estimation of intervertebral disc degeneration on magnetic resonance imaging (MRI) is challenging. Qualitative schemes used in clinical practice correlate poorly with pain and quantitative techniques have not entered widespread clinical use.
Chamoli, Uphar   +5 more
core   +1 more source

Sauteur d'Alfort rabbit‐like locomotory disturbances and eye disorders in two pet rabbits—‘handstand rabbits’

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract Homozygous sauteur d'Alfort rabbits have a splicing‐site mutation in the RAR‐related orphan receptor B (RORB) gene that causes changes in their locomotion. These rabbits sometimes walk on their thoracic limbs, especially at higher speeds. They also experience additional abnormalities, including eye alterations such as blindness due to retinal ...
Kerstin Müller   +4 more
wiley   +1 more source

Poly-3-hydroxybutyrate-co-3-hydroxyvalerate(PHBV)-Polyethylene glycol 20k(PEG20k) as a promising delivery system for PT2399 in the treatment of disc degeneration

open access: yesJournal of Biological Engineering
Disc degeneration often leads to a highly prevalent symptom known as low back pain. Healthy nucleus pulposus tissue exhibited a hypoxic environment devoid of blood vessels, while degenerated nucleus pulposus experienced hypoxic deterioration and the ...
Zhencong Li   +9 more
doaj   +1 more source

Traditional Chinese medicine promotes the resorption of herniated intervertebral discs by regulating autophagy and apoptosis

open access: yesPharmacological Research - Modern Chinese Medicine, 2022
Yiqi Huoxue Decoction (abbreviated as YH in this paper) is a well-accepted traditional Chinese medicine formula used for the treatment of lumbar disc herniation (LDH).
Feng Mao   +9 more
doaj  

Sa12b-Modified Functional Self-Assembling Peptide Hydrogel Enhances the Biological Activity of Nucleus Pulposus Mesenchymal Stem Cells by Inhibiting Acid-Sensing Ion Channels

open access: yesFrontiers in Cell and Developmental Biology, 2022
Various hydrogels have been studied for nucleus pulposus regeneration. However, they failed to overcome the changes in the acidic environment during intervertebral disc degeneration.
Letian Han   +15 more
doaj   +1 more source

Total reaction cross section on a deuteron target and the eclipse effect of the constituent neutron and proton [PDF]

open access: yes, 2020
Background: Eclipse effect of the neutron and proton in a deuteron target is essential to correctly describe high-energy deuteron scattering. The nucleus-deuteron scattering needs information not only on the nucleus-proton but also the nucleus-neutron interaction, for which no direct measurement of the nucleus-neutron cross sections is available for ...
arxiv   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han   +8 more
wiley   +1 more source

Intervertebral Disc Degeneration and Regeneration: New Molecular Mechanisms and Therapeutics

open access: yesCells
The intervertebral disc (IVD) is a soft tissue that constitutes the spinal column together with the vertebrae, and consists of the central nucleus pulposus (gelatinous tissue) and the annulus fibrosus (rich in fibrous tissue) that surrounds the nucleus ...
Hideki Sudo
doaj   +1 more source

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