Results 121 to 130 of about 473,018 (289)

Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration

open access: yesCell Proliferation, 2019
Intervertebral disc degeneration (IDD) is a common cause of low back pain, which inflicts more global disability than any other condition. Although IDD was deemed to be a natural process that comes with ageing, a growing body of evidence suggested that ...
Zheng Li   +5 more
semanticscholar   +1 more source

Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells

open access: yesAging Cell, 2019
Aging is a major risk factor of intervertebral disc degeneration and a leading cause of back pain. Pathological changes associated with disc degeneration include the absence of large, vacuolated and reticular‐shaped nucleus pulposus cells, and appearance
S. Mohanty   +4 more
semanticscholar   +1 more source

Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This review provides an intriguing review of the recent advancements, challenges, and future perspectives regarding the application of piezoelectric scaffolds in tissue regeneration. The detailed exposition is anticipated to propel the advancement of personalized and intelligent piezoelectric implants, thereby fostering significant progress in this ...
Xiaoling Deng   +7 more
wiley   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou   +7 more
wiley   +1 more source

First Report of Intervertebral Disc Calcification in a Black Child in Sub‐Saharan Africa

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
Standard X‐ray of the cervical spine from the front and in profile. Blurred appearance of the C2–C3 and C3–C4 vertebral endplates and calcification (orange arrow) in the intervertebral disc of C2–C3. ABSTRACT We report an intervertebral disc calcification in a Black African child who had consulted us for neck pain. The diagnosis of C2–C3 intervertebral
Yamyelle Enselme Zongo   +7 more
wiley   +1 more source

Association Between Sarcopenia and the Long‐Term Risk of Intervertebral Disc Degeneration

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Sarcopenia and intervertebral disc degeneration (IDD) are both highly prevalent among the elderly and have a substantial impact on their quality of life. However, the association between sarcopenia and IDD remains unclear. This study aimed to investigate whether sarcopenia is independently associated with an increased risk of IDD in
Jianan Chen   +13 more
wiley   +1 more source

Free Radicals in Health and Disease

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source

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