Results 61 to 70 of about 18,806 (262)
Nature CommunicationsIntervertebral disc degeneration is a natural process during aging and a leading cause of lower back pain. Here, we generate a comprehensive atlas of nucleus pulposus cells using single-cell RNA-seq analysis of human nucleus pulposus tissues (three males
Fan Chen +9 more
doaj +1 more source
MANAJEMEN NYERI PASIEN RAWAT JALAN PADA KASUS HERNIA NUKLEUS PULPOSUS MELALUI CORE STABILITY
Jurnal Vokasi Indonesia, 2014 Herniated nucleus pulposus (HNP) is a situation where the annulus fibrosus along nucleus pulposus protruding into the spinal canal. HNP patients often complain of back pain radiating to the lower limbs, especially when bending activity.
Elsa Roselina +2 more
doaj +1 more source
Concurrent ANNPE and vertebral T‐cell lymphoma in a dog: A case report
Journal of Small Animal Practice, EarlyView.Acute non‐compressive nucleus pulposus extrusion (ANNPE) is a recognised cause of peracute spinal cord injury in dogs, involving sudden extrusion of non‐degenerated nucleus pulposus with minimal compression. While often linked to vigorous activity, its triggers remain unclear.
A. Mondino +5 more
wiley +1 more source
Orthopaedic Surgery, Volume 17, Issue 5, Page 1464-1477, May 2025.This study compares the biomechanical effects of three anterior fixation systems in thoracolumbar surgery—HXTL, NHXTL, and Medtronic's CD Horizon ANTERIOR. Finite element analysis evaluates stress and displacement across vertebral bodies and support structures under varying load conditions. Results indicate the HXTL system minimizes nail–rod stress yet
Xuehai Jia +7 more
wiley +1 more source
Orthopaedic Surgery, Volume 17, Issue 5, Page 1418-1432, May 2025.Developed a staging system for adjacent segment disease based on degeneration characteristics. Verified the feasibility and reliability of stage‐guided surgical decision‐making through surgical data, radiological data, and follow‐up data. This staging system was closely correlated with intervertebral disc degeneration and disc height while also ...
Changpeng Qu +9 more
wiley +1 more source
Degenerative cervical spine disease – pathogenesis and symptoms
Studia Medyczne, 2020 Cervical discopathy is a degenerative process in the intervertebral disc and the structure of the fibrous ring. Due to the processes of proteoglycan breakdown and collagen structure, the nucleus pulposus is dehydrated and susceptible to the damaging ...
Sebastian Podlewski +2 more
doaj +1 more source
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy [PDF]
, 2020 Gaocai Li +17 more
openalex +1 more source
Progress of Programmed Cell Death in Steroid‐Induced Osteonecrosis of the Femoral Head
Orthopaedic Surgery, EarlyView.Steroid‐induced osteonecrosis of the femoral head is a severe osteoarticular condition resulting from glucocorticoid overuse, characterized by femoral head bone structure collapse and cell death, now predominant among nontraumatic femoral head necroses.
Zhi Kong, Chao Han
wiley +1 more source
Cellular Physiology and Biochemistry, 2016 Background: Spinal degenerative diseases are a major health problem and social burden worldwide. Intervertebral disc degeneration (IDD) is the pathological basis of spinal degenerative diseases and is characterized by loss of nucleus pulposus cells due ...
Jin Feng Ma +4 more
doaj +1 more source