Results 71 to 80 of about 494,442 (303)
Background Increasing studies have shown degeneration of nucleus pulposus cells (NPCs) as an critical part of the progression of intervertebral disc degeneration (IVDD).
Peigeng Wang, Zhencong Li, Dongping Ye
doaj +1 more source
Background: It has been demonstrated that vitamin D deficiency is associated with an increased risk of patients developing lumbar disc herniation. However, intervertebral disc degeneration caused by active vitamin D deficiency has not been reported. Thus,
Peng Wang+5 more
doaj
Nucleus pulposus explant culture model [PDF]
AbstractMany of the therapeutic interventions for intervertebral disc degeneration attempt to repopulate the nucleus pulposus (NP) tissue; however, NP cells are heterogeneous and not well characterized. To address this, we have investigated the morphology, extracellular gene and protein expression, and apoptosis changes in NP explants cultured in vitro
Gang Feng+4 more
openaire +3 more sources
Stiffness of photocrosslinkable gelatin hydrogel influences nucleus pulposus cell propertiesin vitro
A key early sign of degenerative disc disease (DDD) is the loss of nucleus pulposus (NP) cells (NPCs). Accordingly, NPC transplantation is a treatment strategy for intervertebral disc (IVD) degeneration. However, in advanced DDD, due to structural damage
Panpan Xu+8 more
semanticscholar +1 more source
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan+8 more
wiley +1 more source
Nucleus-nucleus potential with shell-correction contribution [PDF]
The full relaxed-density potential between spherical nuclei is considered as a sum of the macroscopic and shell-correction contributions. The macroscopic part of the potential is related to a nucleus-nucleus potential obtained in the framework of the extended Thomas-Fermi approach with the Skyrme and Coulomb forces and the relaxed-density ansatz for ...
arxiv +1 more source
Reconstructing the impact parameter of proton-nucleus and nucleus-nucleus collisions [PDF]
In proton-nucleus and nucleus-nucleus collision experiments, one determines the centrality of a collision according to the multiplicity or energy deposited in a detector. This serves as a proxy for the true collision centrality, as defined by the impact parameter.
arxiv +1 more source
The cell cycle regulator p16 is known as a biomarker and an effector of aging. However, its function in intervertebral disc degeneration (IVDD) is unclear.
Hui Che+11 more
semanticscholar +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
IntroductionThe dynamic disc model (DDM) is a theoretical framework in spine mechanics that theorizes the behavior of the nucleus pulposus within the intervertebral disc under various loads.
Jean-Philippe Deneuville+23 more
doaj +1 more source