Results 81 to 90 of about 494,442 (303)

Poisson’s ratio of nucleus pulposus tissue : comparison of experimental results with a biphasic poroviscoelastic finite element model [PDF]

open access: yes, 2012
This presentation looks at Poisson’s ratio of nucleus pulposus tissue, comparison of experimental results with a biphasic poroviscoelastic finite element ...
Farrell, Mark, Riches, Philip
core  

Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition. [PDF]

open access: yes, 2019
Poor solute transport through the cartilage endplate (CEP) impairs disc nutrition and could be a key factor that limits the success of intradiscal biologic therapies.
Dolor, Aaron   +5 more
core   +2 more sources

Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

open access: yesTheranostics, 2019
Objectives: Intervertebral disc degeneration (IDD) is widely accepted as a cause of low back pain and related degenerative musculoskeletal disorders. Nucleus pulposus (NP) cell apoptosis which is related to excessive endoplasmic reticulum (ER) stress in ...
Zhiwei Liao   +9 more
semanticscholar   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study

open access: yesJOR Spine, 2018
Mechanical loading is inherently related to the function and degeneration of the intervertebral disc. We present a series of experiments aimed at measuring the effect of a loading/unloading cycle of the intervertebral disc on the mechanical properties of
Steven V. Beekmans   +3 more
doaj   +1 more source

Subsonic and supersonic nucleus-acoustic solitary waves in thermally degenerate plasmas with heavy nucleus species [PDF]

open access: yesarXiv, 2020
A fully ionized multi-nucleus plasma system (containing thermally degenerate electron species, non-degenerate warm light nucleus species, and low dense stationary heavy nucleus species) is considered. The basic features of thermal and degenerate pressure driven small and arbitrary amplitude subsonic and supersonic nucleus-acoustic solitary waves in ...
arxiv  

Dilepton production from the Color Glass Condensate [PDF]

open access: yesPhys.Rev.D66:094014,2002, 2002
We consider dilepton production in high energy proton-nucleus (and very forward nucleus-nucleus) collisions. Treating the target nucleus as a Color Glass Condensate and describing the projectile proton (nucleus) as a collection of quarks and gluons as in the parton model, we calculate the differential cross section for dilepton production in quark ...
arxiv   +1 more source

Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype [PDF]

open access: yes, 2019
© 2019, The Author(s). To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell ...
Adams, M.A.   +6 more
core   +1 more source

Anisodamine Maintains the Stability of Intervertebral Disc Tissue by Inhibiting the Senescence of Nucleus Pulposus Cells and Degradation of Extracellular Matrix via Interleukin-6/Janus Kinases/Signal Transducer and Activator of Transcription 3 Pathway

open access: yesFrontiers in Pharmacology, 2020
Objectives: Anisodamine (ANI) has been used to treat a variety of diseases. However, the study of ANI in intervertebral disc degeneration (IVDD) is unclear. This study investigated the effects of ANI on degenerative nucleus pulposus cells (NPCs) and IVDD
Ning Tang   +3 more
semanticscholar   +1 more source

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

open access: yesAdvanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang   +13 more
wiley   +1 more source

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