Results 1 to 10 of about 23,701 (235)

4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABA_A Receptor Subtype

Molecules, 2023
The isosteric replacement of the benzene with thiophene ring is a chemical modification widely applied in medicinal chemistry. Several drugs containing the thiophene ring are marketed for treating various pathologies (osteoporosis, peripheral artery ...
Letizia Crocetti, Gabriella Guerrini, Fabrizio Melani, Claudia Vergelli, Maria Paola Giovannoni   +4 more
doaj   +1 more source

Targeting EGFR in Combination with Nutritional Supplements on Antitumor Efficacy in a Lung Cancer Mouse Model

Marine Drugs, 2022
Selenium (Se) and fish oil (FO) exert anti-epidermal growth factor receptor (EGFR) action on tumors. This study aimed to compare the anti-cancer efficacy of EGFR inhibitors (gefitinib and erlotinib) alone and in combination with nutritional supplements ...
Chih-Hung Guo, Wen-Chin Li, Chia-Lin Peng, Pei-Chung Chen, Shih-Yu Lee, Simon Hsia   +5 more
doaj   +1 more source

The Effect of Fermented Kefir as Functional Feed Additive in Post-Weaned Pigs

Fermentation, 2021
The control of the immune system of pigs after weaning is important in pig farming because productivity depends on the survival of the post-weaned pigs.
Woosik Choi, Dang Bao Son, Jeongpyo Hong, Dabeen Jeong, Hee-Chang Kim, Hanki Lee, Joo-Won Suh   +6 more
doaj   +1 more source

Transgenic Canola Oil Improved Blood Omega-3 Profiles: A Randomized, Placebo-Controlled Trial in Healthy Adults

Frontiers in Nutrition, 2022
Long-chain omega-3 polyunsaturated fatty acids (LC-ω3 PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), play key roles in physiological functions and disease prevention.
Xinjie Lois Lin, Joshua Baisley, Anthony Bier, Drasty Vora, Bruce Holub   +4 more
doaj   +1 more source

Text mining datasets of β-hydroxybutyrate (BHB) supplement products’ consumer online reviews

Data in Brief, 2020
The current dataset is obtained by text mining of β-hydroxybutyrate (BHB) supplement products’ consumer online reviews. The text data of 71 BHB products’ consumer reviews were extracted with the aid of the Web Scraper Chrome extension.
Ji Li, Dan Lowe, Luke Wayment, Qingrong Huang   +3 more
doaj   +1 more source

Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators

Molecules, 2023
Positive allosteric modulators (PAMs), negative allosteric modulators (NAMs), silent agonists, allosteric activating PAMs and neutral or silent allosteric modulators are compounds capable of modulating the nicotinic receptor by interacting at allosteric ...
Dina Manetti, Silvia Dei, Hugo R. Arias, Laura Braconi, Alessio Gabellini, Elisabetta Teodori, Maria Novella Romanelli   +6 more
doaj   +1 more source

Influence of Coal Mining Activities on Soil's Agrochemical and Biochemical Properties

Qubahan Academic Journal, 2023
Recultivation of technologically disturbed land is an important objective of environmental protection. The study aimed to examine the impact of the coal mining process on the agrochemical and biochemical parameters of soil.
Svetlana Ivanova, Anna Vesnina, Nataly Fotina, Alexander Prosekov   +3 more
doaj   +1 more source

Nutraceuticals: A Review [PDF]

Dermatology and Therapy, 2018
Skin aging is continuously influenced by various internal and external factors such as the biologic progression of cells, ultraviolet (UV) radiation, tobacco, nutritional deficiencies, and hormonal imbalances that lead to the degradation of skin cells.
Souyoul, Skylar A., Saussy, Katharine P., Lupo, Mary P.   +2 more
openaire   +2 more sources

Oral administration of 6-methylsulfinylhexyl isothiocyanate extracted from wasabi is safe and improves the fatigue and sleep of healthy volunteers

BioPsychoSocial Medicine, 2023
Background This study aimed to conduct a preliminary evaluation of the effects of 6-methylsulfinylhexyl isothiocyanate (6-MSITC) contained in wasabi rhizomes on fatigue and sleep and to examine its safety through overdose study.
Ryota Nakajima, Masanobu Kanou, Masahiko Tokushima, Yoshitaka Iwama, Kei Yamana   +4 more
doaj   +1 more source

Study of Mono and Di-O-caffeoylquinic Acid Isomers in Acmella oleracea Extracts by HPLC-MS/MS and Application of Linear Equation of Deconvolution Analysis Algorithm for Their Characterization

Pharmaceuticals, 2023
Chlorogenic acids, the esters of caffeic and quinic acids, are the main phenolic acids detected in Acmella oleracea extracts and have gained increasing interest in recent years due to their important biological activities.
Maria Bellumori, Marco Pallecchi, Beatrice Zonfrillo, Luigi Lucio, Marta Menicatti, Marzia Innocenti, Nadia Mulinacci, Gianluca Bartolucci   +7 more
doaj   +1 more source