Results 221 to 230 of about 89,672 (304)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Artificial Intelligence-Enabled Ingredient Substitution in Food Systems: A Review and Conceptual Framework for Sensory, Functional, Nutritional, and Cultural Optimization. [PDF]

Foods
Oz E, Oz F.
europepmc   +1 more source

Corrigendum to "Research note: Effects of fermented vegetable extract supplementation via drinking water on growth performance, immune function, and antioxidant status in broiler chickens" [Poultry Science, Volume 104/issue 10, 105583]. [PDF]

Poult Sci
Yu H, Khanum S, Ali MM, Rahman A, Hayat Z, Waqas M, Riaz R, Sajid M, Khan M, Zafar MS.   +9 more
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Untargeted metabolomics approaches challenge the nutri-score FOPNL system in soluble cocoa products. [PDF]

NPJ Sci Food
Palma-Morales M, Rangel-Huerta OD, Urrialde R, Rodríguez-Pérez C.   +3 more
europepmc   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Is chubby cute? Clinical perspectives on obesity prevention and metabolic health in Macau. [PDF]

Front Public Health
Mio W, Tan C, Tou P, Cheang S, Cheang C.
europepmc   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

The Need for Uniform Labeling Regulations for Monosodium Glutamate to Address Health Risks and Consumer Protection. [PDF]

Cureus
Purvez A, Valentine MC.
europepmc   +1 more source