Results 61 to 70 of about 21,480 (235)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Adaptability, yield and in vitro evaluation of some promising silage maize hybrids under tropical climate

open access: yesIndian Journal of Animal Sciences, 2019
The study was conducted to assess adaptability, yield and in vitro evaluation of some promising silage maize hybrids (LG 32.01, LG 34.04 and BL 4121) grown under tropical climate.
JASPAL SINGH HUNDAL   +3 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

RELATIONSHIP OF BREAST MILK LEPTIN WITH MATERNAL AND INFANT ADIPOSITY

open access: yesARYA Atherosclerosis, 2010
INTRODUCTION: Leptin, the product of the obese gene (ob), is synthesized by adiposetissue and contributes to the regulation of energy homeostasis and food intake. Recently,immunoreactive leptin was reported to be present in human milk.
Mohammad Khalili   +6 more
doaj  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Awareness and Understanding Amongst New Zealand Health Professionals of Venison in a Healthy Diet

open access: yesProceedings, 2019
New Zealand (NZ) farmed venison is available for NZ consumers, and exported globally, including to Belgium, Netherlands, Germany and the United States of America (USA). [...]
Julie North, Claire Owen
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

PLASMA IRON IS ASSOCIATED WITH LIPID PEROXIDATION IN WOMEN

open access: yesARYA Atherosclerosis, 2010
  Abstract INTRODUCTION: It has been suggested that the risk of coronary heart disease increases with increase of body iron stores. Free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids. The aim
Farshad Amirkhizi   +6 more
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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