Results 121 to 130 of about 5,743 (215)

Expressionsregulation der organischen Anionentransporter OAT1 und OAT3 im Ischämie-Reperfusions-Modell

, 2018
Recently, we gained evidence that impairment of rOat1 and rOat3 expression induced by ischemic acute kidney injury (AKI) is mediated by COX metabolites and this suppression might be critically involved in renal damage. Basolateral organic anion uptake into proximal tubular cells after model ischemia and reperfusion (I/R) was investigated by fluorescein
openaire   +2 more sources

Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide

Drug Design, Development and Therapy, 2015
Hyeon-Uk Jeong,1 Mihwa Kwon,2 Yongnam Lee,3 Ji Seok Yoo,3 Dae Hee Shin,3 Im-Sook Song,2 Hye Suk Lee1 1College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea; 2College of Pharmacy and Research Institute of Pharmaceutical Sciences ...
Jeong HU, Kwon M, Lee Y, Yoo JS, Shin DH, Song IS, Lee HS   +6 more
doaj  

Flavonoid Interactions with Renal Organic Anion Transporters OAT1 and OAT3: Structure-Activity Relationships and Clinical Implications. [PDF]

Int J Mol Sci
Tong K, Ye P, Kaneda-Nakashima K, Zhang H, Wei L.   +4 more
europepmc   +1 more source

Dual mechanisms of a purified root extract of <i>Paeonia lactiflora</i> Pall. in regulating uric acid homeostasis: inhibition of hepatic synthesis and promotion of renal excretion in hyperuricemic rat models. [PDF]

Front Pharmacol
Jin T, Xu R, Jiang Z, Ma J, Li N.
europepmc   +1 more source

Sepsis-induced acute kidney injury by standardized colon ascendens stent peritonitis in rats - a simple, reproducible animal model [PDF]

, 2014

core   +1 more source

Multitargeting Pt(IV) Anticancer Prodrugs Bearing Mono- and Bis-Probenecid Ligands in Axial Positions: Synthesis and Evaluation of Biological Activity. [PDF]

Pharmaceuticals (Basel)
Qiu P, Zhang Y, Dou Y, Cheng Z, Wu X, Zhang S, Wang F, Wu K.   +7 more
europepmc   +1 more source

Assignment of the 2P domain, acid-sensitive potassium channel OAT1 gene KCNK3 to human chromosome bands 2p24.1-->p23.3 and murine 5B by in situ hybridization. [PDF]

, 1999
Bray-Ward, P, Gallagher, PG, Goldstein, SA, Manjunath, NA   +3 more
core  

Genome-wide association studies and traditional Chinese medicine in hyperuricemia: current evidence and mechanistic insights. [PDF]

Front Pharmacol
Yang L, Liu J, Luo S, Deng Y.
europepmc   +1 more source

Human OAT1, OAT3, OAT4 and OATP1A2 Facilitate the Renal Accumulation of Ochratoxin A. [PDF]

Pharmaceutics
Mahadeo A, Tsang YP, Zheng AR, Arnzen S, Rodriguez AG, Warren MS, Gáborik Z, Kelly EJ.   +7 more
europepmc   +1 more source

An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs. [PDF]

Toxicology
Sakolish C, Lin HC, Moyer HL, Ford LC, Christen CH, Wetmore BA, DeVito MJ, Hewitt P, Ferguson SS, Raad F, Rusyn I, Chiu WA.   +11 more
europepmc   +1 more source