Results 31 to 40 of about 1,214 (179)
Protein and alkaloid patterns of the floral nectar in some solanaceous species [PDF]
, 2015 The family Solanaceae includes several melliferous plants, which tend to produce copious amounts of nectar. Floral nectar is a chemically complex aqueous solution, dominated by sugars, but minor components such as amino acids, proteins, flavonoids and ...
Bacskay, Ivett +5 more
core +1 more source
Neuroprotective Effects of Antidotes in Soman-Poisoned Rats
Acta Medica, 1999 1. The neuroprotective effects of antidotes (atropine, obidoxime/atropine mixture, HI-6/atropine mixture) on rats poisoned with soman at a sublethal dose (48 μg/kg i.m.; 60% of LD50 value) were studied.
Jiří Kassa, Marie Koupilová
doaj +1 more source
Kvalitativna procjena eliminacije TCP-a i TAMORF-a iz organizma štakora metodom GC-MS [PDF]
, 2010 Nerve agents are highly toxic organophosphorus (OP) compounds. They inhibit acetylcholinesterase (AChE), an enzyme that hydrolyses acetycholine (ACh) in the nervous system.
A. Lucić Vrdoljak +20 more
core +2 more sources
Therapeutic Efficacy of Different Antidotal Mixtures Against Poisoning with GF-Agent in Mice
Acta Medica, 2004 The toxicity of cyclohexyl methylphosphonofluoridate (GF-agent; cyclosarin) and therapeutic efficacy of four oximes (trimedoxime, methoxime, obidoxime and HI-6) in combination with atropine or benactyzine (BNZ) was studied in mice.
Lucie Bartošová +3 more
doaj +1 more source
The Influence of Oxime Selection on the Efficacy of Antidotal Treatment of Soman-Poisoned Rats
Acta Medica, 2002 1. The influence of some acetylcholinesterase reactivators (HI-6, obidoxime, pralidoxime) on the efficacy of antidotal treatment to eliminate soman-induced disturbance of respiration and circulation and to protect experimental animals poisoned with ...
Jiří Kassa, Josef Fusek
doaj +1 more source
Vibrational analysis of 1-methyl-pyridinium-2-aldoxime- and 1-methyl-pyridinium-4-aldoxime chloride [PDF]
, 2011 Pyrimidinium aldoximes are administered in cases of acute organophosphate poisoning. Since questions regarding their morphology and active conformation in the solid state are still open, an effort was made to establish correspondence between their ...
Foretić, Blaženka +2 more
core +1 more source
Drug Testing and Analysis, Volume 12, Issue 7, Page 938-947, July 2020., 2020 A HPLC‐DAD method was developed and validated for single and simultaneous quantification of obidoxime, pralidoxime, and HI‐6 for pharmacokinetic studies and clinical samples. Abstract Oximes such as pralidoxime (2‐PAM), obidoxime (Obi), and HI‐6 are the only currently available therapeutic agents to reactivate inhibited acetylcholinesterase (AChE) in ...
Tamara Kranawetvogl +3 more
wiley +1 more source
Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering
Advanced Science, Volume 7, Issue 1, January 8, 2020., 2020 Butyrylcholinesterase (BChE)‐polymer‐oxime conjugates are synthesized by in situ atom transfer radical polymerization and azide‐alkyne “click” chemistry. The conjugate's activity depends on the electrostatic properties of the polymers and the oxime to BChE ratio.
Libin Zhang +7 more
wiley +1 more source
Organophosphorus Nerve Agents: Types, Toxicity, and Treatments
Journal of Toxicology, Volume 2020, Issue 1, 2020., 2020 Organophosphorus compounds are extensively used worldwide as pesticides which cause great hazards to human health. Nerve agents, a subcategory of the organophosphorus compounds, have been produced and used during wars, and they have also been used in terrorist activities.
Sudisha Mukherjee +2 more
wiley +1 more source
THE EFFECTS OF OXIMES IN THE ASSAY OF ACETYLCHOLINESTERASE ACTIVITY IN LYSED ERYTHROCYTES IN VITRO [PDF]
Acta Medica Iranica, 1997 Organophosphorus compounds are known to inhibit the esteratic site of acetylcholinesterase by phosphorylation. The phosphorylated esteratic site of acetylcholinesterase undergoes hydrolytic regeneration at a slow or negligible rate.
M. Abdollahi. +1 more
doaj +1 more source