Results 181 to 190 of about 55,164 (304)

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Clostridium perfringens Type A Isolated from Intestinal Contents of Alpaca. [PDF]

Microorganisms
Ren H, Jia Q, Gao S, Yang H, Zhang S, Fan R.   +5 more
europepmc   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

In Vitro Analysis of TWEAK/Fn14 Axis in the Blood-Brain Barrier Models during Oxygen-Glucose Deprivation and Reoxygenation. [PDF]

Mol Neurobiol
Sampedro-Viana A, Alonso-Alonso ML, Castillo J, Hervella P, Álvarez E, Burek M, Iglesias-Rey R.   +6 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

The Breakdown of Neurovascular Barriers: Molecular Mechanisms of Tight Junction Dysfunction. [PDF]

Mol Neurobiol
Gopal SS, Kaur M, Lanzkron S, Srivastava AK.   +3 more
europepmc   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, Volume 7, Issue 2, March 2026.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

The Protective Effects of Membrane‐Separated Ripe Pu‐Erh Tea Extracts Against Chronic Alcoholic Liver Injury

Food Frontiers, Volume 7, Issue 2, March 2026.
In this study, we investigated the protective effects of different membrane‐separated ripe Pu‐erh tea on alcohol‐induced liver injury. The result indicated that ripe Pu‐erh tea separated by a 50 nm ceramic membrane (molecular weight < 300 kDa) has the best effect on preventing ALD.
Sibo Zhao, Jielin Jiang, Yan Liu, Mianhong Xu, Rui Yang, Zhi Yang, Jilin Xie, Zhanggui Ding, Liyong Luo, Liang Zeng   +9 more
wiley   +1 more source

Tight junctions expression is affected by active, inactive, and derivatives of <i>Akkermansia muciniphila</i>. [PDF]

Iran J Microbiol
Ghaderi F, Hajebrahimi Z, Fateh A, Sotoodehnejadnematalahi F, Ahmadi Badi S, Vaezijoze S, Siadat SD.   +6 more
europepmc   +1 more source

Perinatal Gut Dysbiosis Reduces Milk Oligosaccharides via LPS‐Mediated Gut–Mammary Signaling in Mice

Food Frontiers, Volume 7, Issue 2, March 2026.
Maternal gut dysbiosis elevates Gram‐negative bacterial lipopolysaccharide (LPS), which enters circulation and accumulates in mammary tissue. This compromises the blood–milk barrier and suppresses key enzymatic genes, ultimately reducing milk oligosaccharide synthesis and potentially affecting neonatal gut microbiota through breastfeeding.
Man‐Lin Zhou, Ye Wang, Yan‐Ling Kang, Bushra Walayat, Bin‐Qi Rui, Qi‐Di Xue, Xi He, Jing‐Yu Yan, Yin‐Hui Liu, Ming Li   +9 more
wiley   +1 more source