Results 161 to 170 of about 75,125 (295)
The Journal of Physiology, EarlyView.Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov +8 more
wiley +1 more source
FAK signaling suppression by OCT4-ITGA6 mediates the effectively removal of residual pluripotent stem cells and enhances application safety [PDF]
Wenpeng Song +12 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 323-338, July 2026.ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang +12 more
wiley +1 more source
Liver International, Volume 46, Issue 7, July 2026.ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley +1 more source
δ‐Tocotrienol Inhibits Migration and Reduces Chemoresistance in Ovarian Cancer Stem‐Like Cells
eFood, Volume 7, Issue 3, June 2026.δ‐Tocotrienol targets ovarian cancer stem cell populations and suppresses stem‐like traits, migration, and chemoresistance, with concomitant downregulation of Akt and NF‐κB signaling. ABSTRACT Ovarian cancer (OC) is the most lethal form of gynecologic malignancies, due to its intrinsic chemoresistance and ability to relapse.
Gaia Giannitti +4 more
wiley +1 more source
Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu +3 more
wiley +1 more source
Suppress the cell growth of cancer stem-like cells (NTERA-2) using Sox2-Oct4 decoy oligodeoxynucleotide−encapsulated niosomes-zinc hybrid nanocarriers under X-irradiation [PDF]
Behrooz Johari +5 more
openalex +1 more source