Results 41 to 50 of about 858,764 (131)

HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation

open access: yesFrontiers in Cell and Developmental Biology, 2020
Odontoblast differentiation is an important process during tooth development in which pre-odontoblasts undergo elongation, polarization, and finally become mature secretory odontoblasts.
Yunyan Zhan   +4 more
doaj   +1 more source

KLF6 facilitates differentiation of odontoblasts through modulating the expression of P21 in vitro

open access: yesInternational Journal of Oral Science, 2022
Multiple signaling pathways are involved in the regulation of cell proliferation and differentiation in odontogenesis and dental tissue renewal, but the details of these mechanisms remain unknown.
Zhuo Chen   +5 more
doaj   +1 more source

The role of osteomodulin on osteo/odontogenic differentiation in human dental pulp stem cells

open access: yesBMC Oral Health, 2019
Background Extracellular matrix secretion and odontoblastic differentiation in human dental pulp stem cells (hDPSCs) are the cellular bases for reparative dentinogenesis.
Wenzhen Lin   +7 more
doaj   +1 more source

The Effect of White Mineral Trioxide Aggregate on Migration, Proliferation, and Odontoblastic Differentiation of Stem Cells from the Apical Papilla [PDF]

open access: yes, 2013
White Mineral Trioxide Aggregate (WMTA) is a biocompatible dental material with osteoinductive and osteogenic properties recommended for use in regenerative endodontic protocols.
Schneider, Robert S.
core   +4 more sources

Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration

open access: yesJournal of Tissue Engineering, 2022
Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang   +8 more
doaj   +1 more source

PER2 Promotes Odontoblastic/Osteogenic Differentiation of Dental Pulp Stem Cells by Modulating Mitochondrial Metabolism

open access: yes, 2023
Human dental pulp stem cells (hDPSCs) possess remarkable self-renewal and multilineage differentiation ability. PER2, an essential circadian molecule, regulates various physiological processes. Evidence suggests that circadian rhythm and PER2 participate
Qi Huang   +3 more
core   +1 more source

Odontoblastic differentiation analysis.

open access: yes, 2013
Real-time PCR analysis of odontoblastic differentiation of untransfected, AdEGFP-transfected and AdShh-transfected hDPCs at days 3, 6, and 9, respectively. (A) Ptc-1; (B) Smo; (C) Gli 1; (D) Gli 2; (E) Gli 3; (F) OCN; (G) DMP-1; (H) DSPP. (n = 3 for each
Lunguo Xia (411945)   +7 more
core   +1 more source

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang   +3 more
wiley   +1 more source

SHED, PRF, and Chitosan as Three-Dimensional of Tissue Engineering for Dental Pulp Regeneration

open access: yesDental Hypotheses, 2021
The gold standard for pulpitis irreversible treatment is root canal treatment. However, it caused the loss of tooth vitality. To restore tooth vitality, materials that have regenerative ability in the pulp is needed.
Kelvin Alfan Nola Anggrarista   +4 more
doaj   +1 more source

The role of thymosin beta 4 on odontogenic differentiation in human dental pulp cells.

open access: yesPLoS ONE, 2013
We recently reported that overexpression of thymosin beta-4 (Tβ4) in transgenic mice promotes abnormal hair growth and tooth development, but the role of Tβ4 in dental pulp regeneration was not completely understood.
Sang-Im Lee   +4 more
doaj   +1 more source

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