Results 61 to 70 of about 858,764 (131)

Table1_Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.DOCX

, 2022
Human dental pulp stem cells (hDPSCs) have been a focus of pulp regeneration research because of their excellent odontogenic potential and availability.
Rui Li (4631), Yi Li (1144), Yuandong Xie (13763911), Xinchen Liu (12511206), Kai Zhang (102844), Jinjin Lu (11769557), Shilei Ni (7443521)   +6 more
core   +1 more source

Periodontal considerations during orthodontic intrusion and extrusion in healthy and reduced periodontium

Periodontology 2000, EarlyView.
Abstract In patients with advanced periodontal disease, pathological tooth migration may occur, which may require subsequent orthodontic treatment for both aesthetic and functional purposes. When planning orthodontic treatment mechanics, intrusive or extrusive forces are frequently indicated.
Gregory S. Antonarakis, Alkisti Zekeridou, Stavros Kiliaridis, Catherine Giannopoulou   +3 more
wiley   +1 more source

β-catenin promotes odontoblastic differentiation through activation of Runx2.

, 2014
mRNA level (A) and protein expression (B) of Runx2 in DPCs transfected with shRNA-NT or shRNA-β-cat. Effects of the activation of β-catenin by LiCl treatment on the expression of Runx2 at mRNA level (C) and protein expression (D).
Yong Zheng (420246), Yun Niu (85792), Nana Han (521517), Ran Li (57928), Xianyu Li (492675), Qi Zhang (28502), Mi Zhou (9884)   +6 more
core   +1 more source

Expression Pattern Of Rad54b In Odontoblastic Differentiation And Reparative Dentinogenesis

International Dental Journal
Aim or purpose: To investigate the expression pattern of RAD54B, a homologous recombination accessory factor, in odontoblastic differentiation and reparative dentinogenesis and explore its role in the odontoblastic differentiation of human dental pulp ...
Pei Huang, Chen Zhang
doaj   +1 more source

Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration

International Journal of Oral Science, 2022
BMP7 as a regenerative signaling molecule mediates stem cell migration and odontoblastic differentiation (a) and as a pro-angiogenic factor promotes revascularization of endothelial cells (b). Collagen gel supports cell adhesion, spreading, and viability
Cheng Liang, Qingqing Liang, Xun Xu, Xiaojing Liu, Xin Gao, Maojiao Li, Jian Yang, Xiaotao Xing, Haisen Huang, Qi Tang, Li Liao, Weidong Tian   +11 more
doaj   +1 more source

Involvement of M1/M2 Macrophage Polarization in Reparative Dentin Formation

Life, 2022
In cases in which dental pulp tissue is accidentally exposed, direct pulp capping is often performed to induce reparative dentin formation. Although macrophages are essential for the inflammatory response and tissue repair, the emergence pattern and the ...
Masataka Kadowaki, Shinichiro Yoshida, Tomohiro Itoyama, Atsushi Tomokiyo, Sayuri Hamano, Daigaku Hasegawa, Hideki Sugii, Hiroshi Kaneko, Risa Sugiura, Hidefumi Maeda   +9 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Image_1_circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046.TIF

, 2022
circular RNAs (circRNAs) is a broad and diverse endogenous subfamily of non-coding RNAs, regulating the gene expression by acting as a microRNA (miRNA) sponge.
Yue Zhang (30585), Guobin Yang (420939), Guohua Yuan (420938), Hao Zhang (15339)   +3 more
core   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, Volume 13, Issue 57, 14 October 2026.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways

Stem Cell Research & Therapy, 2022
Background Human dental pulp stem cells (hDPSCs) have received widespread attention in the fields of tissue engineering and regenerative medicine. Although amphiregulin (AREG) has been shown to play a vital function in the biological processes of various
Junqing Li, Zhihua Wang, Juan Wang, Qian Guo, Yi Fu, Zihan Dai, Minghao Wang, Yu Bai, Xin Liu, Paul R. Cooper, Jiayuan Wu, Wenxi He   +11 more
doaj   +1 more source