Results 21 to 30 of about 858,764 (131)

LncRNA H19 promotes odontoblastic differentiation of human dental pulp stem cells by regulating miR-140-5p and BMP-2/FGF9 [PDF]

Stem Cell Research & Therapy, 2020
Background Increasing evidence has revealed that long non-coding RNAs (lncRNAs) exert critical roles in biological mineralization. As a critical process for dentin formation, odontoblastic differentiation is regulated by complex signaling networks.
Jialin Zhong, Xinran Tu, Yuanyuan Kong, Liyang Guo, Baishun Li, Wenchao Zhong, Ying Cheng, Yiguo Jiang, Qianzhou Jiang   +8 more
doaj   +2 more sources

Potential role of dental pulp stem cells conditioned medium for odontoblastic differentiation [PDF]

Biological Research, 2022
Background Functional bioengineered tooth regeneration using autologous or allogeneic alternative differentiated cells sources are thought to have a great potential in replacing conventional dentures.
Benson Koh, Farynna Hana Ab Rahman, Najwa Amira Matlan, Manissha Rajan, Aimi Yasmin Musta’ain, Mohamad Ridhwan Mohd Jeffry Lee, Roszalina Ramli, Siti Salmiah Mohd Yunus, Ruszymah Binti Hj Idrus, Muhammad Dain Yazid   +9 more
doaj   +2 more sources

circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046 [PDF]

Frontiers in Physiology, 2022
circular RNAs (circRNAs) is a broad and diverse endogenous subfamily of non-coding RNAs, regulating the gene expression by acting as a microRNA (miRNA) sponge.
Yue Zhang, Hao Zhang, Guohua Yuan, Guobin Yang   +3 more
doaj   +2 more sources

Changes in SIRT gene expression during odontoblastic differentiation of human dental pulp cells

Restorative Dentistry & Endodontics, 2015
Objectives The aim of this study was to investigate the expression of 7 different sirtuin genes (SIRT1-SIRT7) in human dental pulp cells (HDPCs), and to determine the role of SIRTs in the odontoblastic differentiation potential of HDPCs.
Young-Eun Jang, Su-Hee Go, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang   +6 more
doaj   +2 more sources

KPNB1-ATF4 induces BNIP3-dependent mitophagy to drive odontoblastic differentiation in dental pulp stem cells [PDF]

Cellular & Molecular Biology Letters
Background Differentiating dental pulp stem cells (DPSCs) into odontoblasts is a critical process for tooth self-repair and dentine‒pulp engineering strategies in the clinic.
Zeying Zhang, Di Yang, Xiaoyuan Yan, Qiujing Qiu, Jiajie Guo, Lihong Qiu   +5 more
doaj   +2 more sources

Promotive Effect of FBXO32 on the Odontoblastic Differentiation of Human Dental Pulp Stem Cells. [PDF]

Int J Mol Sci, 2023
Odontoblastic differentiation of human dental pulp stem cells (hDPSCs) is crucial for the intricate formation and repair processes in dental pulp. Until now, the literature is not able to demonstrate the role of ubiquitination in the odontoblastic ...
Xu K, Liu Q, Huang W, Chu Y, Fan W, Liu J, He Y, Huang F.   +7 more
europepmc   +2 more sources

Effect of CRABP2 on the proliferation and odontoblastic differentiation of hDPSCs

Brazilian Oral Research, 2017
: Cellular retinoic acid-binding protein 2 (CRABP2) has been detected in several organs during embryonic development. Recent studies have demonstrated that CRABP2 plays important roles in the retinoic acid, β-catenin and Notch signaling pathways, as well
Yanhong Yan, Shengcai Qi, Shi-qiang Gong, Guangwei Shang, Yumei Zhao   +4 more
doaj   +2 more sources

Vacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Our previous studies have revealed that a dominant mutation in vacuolar protein sorting 4B (VPS4B), a member of the AAA ATPase family, causes dentin dysplasia type I.
Yuhua Pan, Ting Lu, Ling Peng, Zhao Chen, Meiyi Li, Kaiying Zhang, Fu Xiong, Buling Wu   +7 more
doaj   +2 more sources

Decreasing NF-κB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines. [PDF]

PLoS ONE, 2015
Inflammatory response in the dental pulp can alter the collagen matrix formation by dental pulp stem cells and lead to a delay or poor healing of the pulp.
Neda S T Hozhabri, M Douglas Benson, Michael D Vu, Rinkesh H Patel, Rebecca M Martinez, Fatemeh N Nakhaie, Harry K W Kim, Venu G Varanasi   +7 more
doaj   +2 more sources

FTO Positively Regulates Odontoblastic Differentiation via SMOC2 in Human Stem Cells from the Apical Papilla under Inflammatory Microenvironment. [PDF]

Int J Mol Sci
Odontoblastic differentiation of human stem cells from the apical papilla (hSCAPs) is crucial for continued root development and dentin formation in immature teeth with apical periodontitis (AP).
Huang Q, Sun Y, Huang W, Zhang F, He H, He Y, Huang F.   +6 more
europepmc   +2 more sources