Results 41 to 50 of about 18,767 (302)

On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling

Frontiers in Cell and Developmental Biology, 2023
Heparan sulfate proteoglycans (HSPGs) surround the surface of odontoblasts, and their modification affects their affinity for Wnt ligands. This study proposes applying Matching Transformation System® (MA-T), a novel chlorinated oxidant, to enhance ...
Toshihiro Inubushi, Nag Priyanka, Masakatsu Watanabe, Yusuke Takahashi, Shinnosuke Kusano, Hiroshi Kurosaka, Silvana Papagerakis, Silvana Papagerakis, Silvana Papagerakis, Silvana Papagerakis, Petros Papagerakis, Petros Papagerakis, Petros Papagerakis, Petros Papagerakis, Mikako Hayashi, Takashi Yamashiro   +15 more
doaj   +1 more source

Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors [PDF]

Restorative Dentistry & Endodontics, 2023
ObjectivesThe present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP).Materials and MethodsThe following groups were compared ...
Douglas Augusto Roderjan, Rodrigo Stanislawczuk, Diana Gabriela Soares, Carlos Alberto de Souza Costa, Michael Willian Favoreto, Alessandra Reis, Alessandro D. Loguercio   +6 more
doaj   +1 more source

Odontoblast morphology and dental repair [PDF]

Journal of Dentistry, 2003
To investigate the changes in morphology and activity of pulp odontoblasts in response to cavity restoration variables and patient factors.Class V non exposed cavities were prepared in the intact 1st or 2nd premolar teeth of 27 patients, aged between 9 and 17 years-old.
Murray, P.E., About, I., Lumley, P.J., Franquin, J.-C., Windsor, L.J., Smith, A.J.   +5 more
openaire   +3 more sources

Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]

, 2011
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey, Asrari, Barthel, Bègue-Kirn, Cabrera, Camargo, Doug Lobner, Duailibi, D’Souza, Fogal, Franco, Furey, Goldberg, Gronthos, Hansen, Hu, Kalyva, Katherine Pauly, Kaur, Keelan, Kim, Kim, Kymberly Fritz, Lobner, Lovschall, Marcato, Nie, Onishi, Pacheco, Paranjpe, Piani, Piattelli, Ricketts, Rutherford, Stanley, Stockton, Tziafas, Tziafas, Ward, Wood   +39 more
core   +2 more sources

37% Phosphoric Acid Induced Stronger Matrix Metalloproteinase-8 Expression of the Dental Pulp Than 19% Ethylene Diamine Tetraacetic Acid [PDF]

, 2014
Etching agents such as ethylene diamine tetraacetic acid (EDTA) and phosphoric acid which are widely used in adhesive restoration system aimed to increase for retention of restorative materials, may act a chemical irritant that induce inflammation of ...
Fatimatuzzahro, N. (Nadie), Handajani, J. (Juni), Haniastuti, T. (Tetiana)   +2 more
core   +2 more sources

Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer [PDF]

, 2019
Background. Fibronectin type III domain-containing (FNDC) proteins fulfill manifold functions in tissue development and regulation of cellular metabolism.
Adler, Andreas, Aigner, Felix, Becker, Olaf, Biebl, Matthias, Bosma, Madeleen, Pratschke, Johann, Quint, Janina, Spitz, Wolfgang, Stockmann, Martin, Veltzke-Schlieker, Wilfried, Weiss, Sascha, Wizenty, Jonas, Wuensch, Tilo   +12 more
core   +2 more sources

Rho/Rho-associated protein kinase signaling pathway-mediated downregulation of runt-related transcription factor 2 expression promotes the differentiation of dental pulp stem cells into odontoblasts.

Experimental and Therapeutic Medicine, 2018
The present study investigated the role of runt-related transcription factor 2 (Runx2) in regulating the differentiation of human dental pulp stem cells (hDPSCs) into odontoblasts under the mediation of the Rho/Rho-associated protein kinase (ROCK ...
Xiaoqing Huang, Xiaoling Chen, Hongbai Chen, Dongwei Xu, Chen Lin, B. Peng   +5 more
semanticscholar   +1 more source

Axin2-expressing cells differentiate into reparative odontoblasts via autocrine Wnt/β-catenin signaling in response to tooth damage

Scientific Reports, 2017
In non-growing teeth, such as mouse and human molars, primary odontoblasts are long-lived post-mitotic cells that secrete dentine throughout the life of the tooth. New odontoblast-like cells are only produced in response to a damage or trauma.
R. Babb, D. Chandrasekaran, Vitor Carvalho Moreno Neves, P. Sharpe   +3 more
semanticscholar   +1 more source

Slc26a2-mediated sulfate metabolism is important in tooth development

Disease Models & Mechanisms
Yuka Yoshida, Toshihiro Inubushi, Mika Yokoyama, Priyanka Nag, Jun-ichi Sasaki, Ayaka Oka, Tomoya Murotani, Renshiro Kani, Yuki Shiraishi, Hiroshi Kurosaka, Yoshifumi Takahata, Riko Nishimura, Satoshi Imazato, Petros Papagerakis, Takashi Yamashiro   +14 more
doaj   +2 more sources

Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]

, 2020
Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles, Huertas Castaño, Carlos, Pardal Redondo, Ricardo, Vega Moreno, Francisco Manuel   +3 more
core   +1 more source