Results 71 to 80 of about 12,751 (221)

Nanomagnetic-Mediated Drug Delivery for The Treatment of Dental Disease [PDF]

, 2018
Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased
Choi, Seung K., Chuncai, Kong, Dashtimoghadam, Erfan, Depireux, Didier A., Ji, Yadong, Lin, Xiaoying, Masri, Radi, Melo, Mary Anne, Nie, Ahihong, Sultan, Ahmed S., Tayebi, Lobat, Weir, Michael, Xu, Huakun   +12 more
core   +2 more sources

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source

mTORC1 regulates exosomes release from odontoblasts to regulate DPSCs odontoblastic differentiation

, 2022
Abstract Dental pulp stem cells (DPSCs) are the crucial part of dentin-pulp complex regeneration. A further understanding of the mechanism of how DPSCs stay in a quiescent state can contribute to improvements in dentin-pulp complex and dentinogenesis.
Xinghong Luo, Weiqing Feng, Shijiang Huang, Shenghong Miao, Tao Jiang, Qian Lei, Sheng Zhang, Xiaochun Bai, Chunbo Hao, Weizhong Li, Dandan Ma   +10 more
openaire   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

Evaluasi Apoptosis Sel Odontoblas Akibat Paparan Radiasi Ionisasi

Journal of Dentistry Indonesia, 2013
Ionizing radiation that is commonly used in the treatment of head and neck cancer can result in multiple effects, such as cell death (apoptotic or necrotic) and malignant transformation.
Supriyadi Supriyadi
doaj   +1 more source

Gelatinases Cleave Dentin Sialoprotein Intracellularly

Frontiers in Physiology, 2020
Dentin sialoprotein (DSP), the NH2-terminal fragment of dentin sialophosphoprotein (DSPP), is essential for dentin formation and further processed into small fragments inside the odontoblasts. Gelatinases, including matrix metalloproteinases 9 (MMP9) and
Xiaohui Gou, Yifan Xue, Huiwen Zheng, Guobin Yang, Shuo Chen, Zhi Chen, Guohua Yuan   +6 more
doaj   +1 more source

Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries [PDF]

, 2014
Background Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to control the incidence of the largely preventable ...
Blackburn, Corinne, Chin, Judith, Srinivasan, Mythily, Zhao, Alyssa   +3 more
core   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

Enzymes, Dentinogenesis and Dental Caries: a Literature Review

eJournal of Oral Maxillofacial Research, 2014
Objectives: Search in PubMed with keywords “enzymes, dentinogenesis, and dental caries” revealed only 4 items, but when combined with “enzymes, osteogenesis, and osteoporosis” as high as 404 items resulted.
Markku Larmas, George K. B. Sándor
doaj   +1 more source

Crosstalk between nuclear factor I-C and transforming growth factor-β1 signaling regulates odontoblast differentiation and homeostasis. [PDF]

PLoS ONE, 2011
Transforming growth factor-β1 (TGF-β1) signaling plays a key role in vertebrate development, homeostasis, and disease. Nuclear factor I-C (NFI-C) has been implicated in TGF-β1 signaling, extracellular matrix gene transcription, and tooth root development.
Dong-Seol Lee, Won-Joon Yoon, Eui Sic Cho, Heung-Joong Kim, Richard M Gronostajski, Moon-Il Cho, Joo-Cheol Park   +6 more
doaj   +1 more source