Results 171 to 180 of about 54,368 (362)
Odorant Inhibition in Mosquito Olfaction. [PDF]
, 2019 How chemical signals are integrated at the peripheral sensory system of insects is still an enigma. Here we show that when coexpressed with Orco in Xenopus oocytes, an odorant receptor from the southern house mosquito, CquiOR32, generated inward (regular)
Chen, Tsung-Yu +8 more
core
Independence of Odor Quality and Absolute Sensitivity in a Study of Aging [PDF]
Young, middle-aged, and senior subjects performed tasks designed to examine whether odor quality discrimination varies independently of sensitivity. One task entailed detection of 2-heptanone and the others AB-X discrimination of quality for sets of 2 ...
Cain, W.S. +3 more
core +2 more sources
Glutathione S-transferases in rat olfactory epithelium: purification, molecular properties and odorant biotransformation [PDF]
, 1993 Nissim Ben‐Arie +2 more
openalex +1 more source
The dark sides of the GPCR tree ‐ research progress on understudied GPCRs
British Journal of Pharmacology, EarlyView.Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf +10 more
wiley +1 more source
Mimicking the Gas-Phase to Transport Odorants through the Nasal Mucus: Functional Insights into Odorant Binding Proteins [PDF]
arXivMammalian odorant binding proteins (OBPs) have long been suggested to transport hydrophobic odorant molecules through the aqueous environment of the nasal mucus. While the function of OBPs as odorant transporters is supported by their hydrophobic beta-barrel structure, no rationale has been provided on why and how these proteins facilitate the uptake ...
arxiv
British Journal of Pharmacology, EarlyView.Graph‐based algorithms that enable efficient computations of all H‐bonds present in structures in entire datasets allow us to dissect H‐bond fingerprints that characterize distinct GPCRs and the structures sampled along their activation. Abstract Changes in structure and dynamics elicited by agonist ligand binding at the extracellular side of G protein
Éva Bertalan +3 more
wiley +1 more source
MoleculesThe coupling of Solid-Phase Microextraction (SPME) technology with gas chromatography (GC) has a well-established and successful history. Traditionally, SPME fibers have been the most popular form thanks to their versatility and the ease with which they ...
Martyna Natalia Wieczorek
doaj +1 more source
An olfactory model for evaluating the larviposition preference of a vector fly
Insect Science, EarlyView.
Jing‐Hua Chen +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel +11 more
wiley +1 more source