Results 121 to 130 of about 14,685,807 (300)
Seed based off-target effects in pooled siRNA screens.
, 2015 (A) An on-target siRNA match is generally understood as a perfect match of nucleotides 1–19 of an 21 nucleotide long siRNA guide strand within the coding sequence of an intended transcript [8].
Hans-Dieter Pohlenz (45029) +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres +6 more
wiley +1 more source
An example showing gaze positions divided into ‘on target’ and ‘off target’.
, 2020 An example showing gaze positions divided into ‘on target’ and ‘off target’.
Johannes M. Zanker (8378667) +1 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Citation: 'off-target effect' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12697 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
openaire +1 more source
“Off-Diagnonal” selection of target cases (TARCC).
, 2019 “Off-Diagnonal” selection of target cases (TARCC).
Donald R. Royall (695528) +1 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Nucleosomes Selectively Inhibit Cas9 Off-target Activity at a Site Located at the Nucleosome Edge
, 2016 Nucleosomes affect Cas9 binding and activity at on-target sites, but their impact at off-target sites is unknown. To investigate how nucleosomes affect Cas9 cleavage at off-target sites in vitro, we used a single guide RNA (sgRNA) that has been ...
Hinz, John M +2 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
Picky off-target gene screening parameters.
, 2013 Picky off-target gene screening parameters.
Peng Liu (120506) +2 more
core +1 more source