Results 131 to 140 of about 5,940 (176)

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1. [PDF]

J Med Chem
Varga M, Ortis F, Del Prado A, Eddershaw A, Scaletti Hutchinson E, Hank EC, Zhou K, Rudolfová N, Dodaro A, Wiita E, Almlöf I, Karsten S, Mamonov K, Ahmed SH, Bentley K, Wallner O, Homan EJ, Scobie M, Helleday T, Prejanò M, Stenmark P, de Vega M, Watson AJB, Michel M.   +23 more
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Mitochondrial DNA Instability and Neuroinflammation: Connecting the Dots Between Base Excision Repair and Neurodegenerative Disease. [PDF]

Genes (Basel)
Pittman MN, Nelsen MB, Thompson MK, Prakash A.   +3 more
europepmc   +1 more source

DNA-Protective Effects of <i>Crocus sativus</i> Stamen Extracts and Their Safety Assessment for Use as Natural Bioactive Agents. [PDF]

Prev Nutr Food Sci
Mamri S, Baddaoui S, Khibech O, Ouahhoud S, Khoulati A, Choukri M, Asehraou A, Saalaoui E.   +7 more
europepmc   +1 more source

Photoprotection for Skin Cancer: What's New. [PDF]

Cancers (Basel)
Gilaberte Y, Ederra-Galé A, García-Alfonso JJ, Gracia-Cazaña T.   +3 more
europepmc   +1 more source

Function of <i>HIF-1α</i> in Regulation of Antioxidative Stress of <i>Tribolium castaneum</i> Under Hypoxia. [PDF]

Insects
Wan Z, Li X, Wang Y, Miao S, Chen Z, Cui S, Lu Y.   +6 more
europepmc   +1 more source

Condition-Specific Transcriptional and Metabolic Divergence in the Dual-Fungal Symbiosis of JinEr Mushroom Under Postharvest Low-Temperature Stress. [PDF]

Genes (Basel)
Li Y, Tang H, Wang F, Lv C, Zhang B, Li H.   +5 more
europepmc   +1 more source

How interactions between oxidized DNA and the NLRP3 inflammasome fuel inflammatory disease. [PDF]

Trends Biochem Sci
Lackner A, Leonidas L, Macapagal A, Lee H, McNulty R.   +4 more
europepmc   +1 more source

Effects of Mechanical Stress on Bone and Cartilage Metabolism: How Mechanical Stress Affects Energy Metabolism in Bone and Cartilage Tissues (Our Research Overview): Mini Review. [PDF]

Int J Mol Sci
Iwata H, Sato S, Somemura S, Takemoto M, Takahashi-Suzuki Y, Sugishita Y, Fujiya H, Haraguchi N, Yudoh K.   +8 more
europepmc   +1 more source

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TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L-mediated OGG1 degradation

Chemico-Biological Interactions, 2022
Pulmonary fibrosis is a highly aggressive and lethal disease that currently lacks effective targeting therapies. Herein, we established a mouse model of pulmonary fibrosis induced by intratracheal instillation of bleomycin (BLM) in wild-type (WT) and 8-oxoguanine DNA glycosylase-1 (OGG1) knockout (Ogg1-/-) mice.
Huayu Ling, Chuge Song, Yaowei Fang, Yu Yin, Zijun Wu, Yahong Wang, Zhiliang Xu, Shenglan Gao, Ao Li, Gang Liu   +9 more
openaire   +2 more sources